Onco Actu du 6 septembre 2016

	1. Biologie
Group Proposes Strategies to Improve Antibodies [The Scientist] An expert committee encourages reagent providers to adopt one of five methods to validate products.
	3.1.1 Tabac - e-cigs
E-cigarette ads may cause children to underestimate smoking risks – study [The Guardian] Study of more than 400 children fuels concerns that exposure to vaping ads could contribute to greater experimentation.
	4.12 Biopsies liquides
The promise of liquid biopsies — could a simple blood test change the future of cancer treatment? [The Institute of Cancer Research] Liquid biopsies could usher in a new era of personalised cancer treatment. Dr Claire Bithell explores the latest research in this fast-moving field.
	5. Traitements
Study opens door to targeted treatments for oesophageal cancer [Cancer Research UK] The scientists, funded by Cancer Research UK and the Medical Research Council, looked at the complete genetic make-up of 129 oesophageal cancers and were able to subdivide the disease into three distinct types based on patterns detected in the DNA of the cancer cells called signatures.
New Drugs for Ovarian Cancer Patients [Wall Street Journal] The drugs, known as PARP inhibitors, are thought to help the body slow the disease’s progression by helping to prevent cancer cells from repairing themselves after chemotherapy treatment, thereby shrinking tumors and delaying relapses.
	5.10 Traitements - Essais
Radiotherapy 'provides no benefit for secondary brain tumours' [NHS Choices] Overall, the results suggest that this treatment approach may need to be reconsidered for people with cancer that has spread to the brain and a poor life expectancy. However, there are a couple of important points to bear in mind.
	6.1 Observation
Annals of Oncology Press Release: Deaths from Ovarian Cancer Decline Worldwide Due to Oral Contraceptive Use [ESMO] The researchers predicted the age-standardised ovarian cancer death rates for France, Germany, Italy, Poland, Spain and the UK, and for the whole of the USA, the EU and Japan up to 2020.
Fall in ovarian cancer deaths worldwide linked to contraceptive pill use [The Guardian] “This mixed pattern in Europe also helps to explain the difference in the size of the decrease in ovarian cancer deaths between the EU and the USA, as many American women also started to use oral contraceptives earlier. Japan, where deaths from ovarian cancer have traditionally been low, now has higher rates in the young than the USA or the EU – again, reflecting infrequent oral contraceptive use.”
	6.5 Médecines alternatives
Please can we give up on complementary, alternative and ‘integrative therapies’ now? [The Conversation] I will be closely watching with interest the next part of the Pain Medicine Symposium from Mayo Clinic Proceedings. I hope the editors were mortified to see the opportunism with which the solid reputation of their publication was exploited by the media beat-up that followed. They have let their readership and their academic integrity down badly with this review.
	6.7.3 DMP
Electronic Health Records: An Unfulfilled Promise and a Call to Action [Annals of Internal Medicine] Sinsky and colleagues confirm what many practicing physicians have claimed: Electronic health records, in their current state, occupy a lot of physicians' time and draw attention away from their direct interactions with patients and from their personal lives.
	6.8 Communication
QS ranks MIT the world’s top university for 2016-17 [MIT News] The QS rankings were based on research quality, graduate employment, teaching quality, and an assessment of the global diversity of faculty and students from 916 institutions worldwide.