Onco Actu du 5 septembre 2016

	3.1.1 Tabac - e-cigs
Tobacco Industry Works to Block Rules on E-Cigarettes [NY Times] With its army of more than 75 lobbyists, tobacco-aligned companies have argued that the F.D.A.’s so-called Deeming Rule could hurt public health by forcing a large share of e-cigarette companies out of business.
	3.3 Prévention - Vaccins
HPV infection rates plummet after vaccine with China the next frontier [The Guardian] A decade after the vaccine was introduced, research shows dramatic success. Australian scientist Ian Frazer says his collaborator Jian Zhou will be ‘vindicated’ when it becomes available in the Chinese market this year.
	4.2 Dép., diag. & prono. - Génome
Considering stakeholders in policy around secondary findings in genomics [Bill of Health] One proposition is to use dynamic forms of consent, which allow decisions around the receipt of secondary findings (and other results) to be changed over time. Using a digital interface, dynamic consent facilitates ongoing communication and would allow participants to change their consent choices at any time—accounting for decisions that are often time- and context-dependent.
	5.10 Traitements - Essais
Lung cancer patients whose tumour has spread to the brain could be spared radiotherapy [Cancer Research UK] The trial found no clear difference in survival and quality of life between the patients who did and didn’t receive whole brain radiotherapy.
Brain radiotherapy 'no benefit' for lung cancer spread [BBC News] A trial of more than 500 patients found that it did not prolong or improve their quality of life any more than other forms of treatment.
	5.12 Immunothérapies
Bristol's Cancer Lead Looks Shakier [Bloomberg] Opdivo is still seen as the dominant drug in immuno-oncology, but how long will that last?
	5.12.2 Immunothérapies - CAR-T
Novartis’ CAR-T chief Azam is leaving, but pharma giant denies any ‘retreat’ is underway [Endpoints News] The company’s response, though, is not likely to change the growing perception that the company is pulling back from the field just as the first CAR-T drugs are being prepped for the FDA.
	6.1 Observation
Modern life is killing our children: Cancer rate in young people up 40 per cent in 16 years [The Telegraph] The rise is most apparent in teenagers and young adults aged between 15 and 24, where the incident rate has risen from around 10 cases in 100,000 to nearly 16.
	6.10 Politiques
The science–policy interface [Science] How do we ensure the effective role of science in public policy-making? This well-worn, long-standing question reflects the fact that the answer is not simple. Later this month in Brussels, scientists and policy-makers will convene at the International Network for Government Science Advice (INGSA) Forum to consider the most promising ways forward.
	6.10.1 Politiques (USA)
Clinton seeks federal panel to determine if drug price hikes are justified [STAT] The plan is lacking some details, but Clinton’s proposed solutions include having the federal government directly purchase drugs, importing competing drugs from other countries, and fining the offending companies to help pay for those actions.
Clinton's New Drug-Price Plan Only a Good Start [Bloomberg] Her plan may not have much impact on the nation's overall drug-spending growth. That is mostly concentrated in high-priced new medicines -- which Clinton's plan is less likely to touch.
Clinton offers plan to curb 'unjustified' price hikes on life-saving drugs [Reuters] Hillary Clinton said on Friday that if elected to the White House she would create an oversight panel to protect U.S. consumers from large price hikes on long-available, lifesaving drugs and to import alternative treatments if necessary, adding to her pledges to rein in overall drug prices.
	6.6 Publications
Are ‘predatory’ publishers’ days numbered? [STAT] According to the US Federal Trade Commission, at least one of these mimics, called the OMICS Group, is a “predatory” publisher. And in a first-ever move for the FTC, the agency is suing the company, saying that they are bilking researchers out of potentially millions of dollars.
	6.7.1 Bioinformatique
Google and UCLH to develop AI to improve cancer therapies [PHG Foundation] Google’s Artificial Intelligence research group announced a new partnership with University College London Hospitals, applying machine learning to radiotherapy treatment for head and neck cancer.
	6.9 Controverses
Hospitals to cut costs by denying surgery to smokers and the obese [The Guardian] Policy documents produced by bosses in the North Yorkshire authority make clear that adult smokers will have elective surgery postponed “for six months or until they’ve stopped smoking for eight weeks”.