jeudi 1 septembre 2016

Onco Actu du 1er septembre 2016

1. Biologie

Widely used brain tumor cell line may not be what researchers thought it was [Retraction Watch]

Venerable brain-cancer cell line faces identity crisis [Nature]

4.12 Biopsies liquides

Tumor DNA in Blood May Signal Response to T-Cell Transfer Immunotherapy [NCI]

5. Traitements

CR UK launches pancreatic cancer trial [Pharma Times]

5.10 Traitements - Essais

Phase III study showed Roche’s cancer immunotherapy TECENTRIQ (atezolizumab) helped people with a specific type of lung cancer live significantly longer compared to chemotherapy [Roche]

Roche's new-drug strategy buoyed by lung-cancer study [Reuters]

5.12.2 Immunothérapies - CAR-T

As Novartis looks to play catch-up in I/O, it ends cell and gene therapy unit [FierceBiotech]

Novartis Disbands T Cell Group But Promises To Press Ahead In CAR-T Race [Xconomy]

Novartis Dissolves CAR-T Unit, Cutting 120 Positions [Forbes]

Novartis to disband cell & gene therapy unit, 120 jobs to go [Reuters]

5.2 Pharma

Takeda Launches Largest Pharmaceutical Company-Sponsored Global Observational Study of Its Kind in Multiple Myeloma [Takeda]

5.2.1 Pharma - Partenariats

Clovis defers Pfizer rucaparib payments to save cash ahead of FDA decision [FierceBiotech]

5.3 Traitements - FDA, EMA,...

FDA to hold long-awaited meeting to review off-label marketing [STAT]

5.3.4 Traitements - AMM (FDA, EMA)

FDA approves Genmab’s ofatumumab for relapsed CLL [European Pharmaceutical Review]

XALKORI® (Crizotinib) Receives Approval In European Union For The Treatment Of Patients With ROS1-Positive Advanced Non-Small Cell Lung Cancer [Pfizer]

5.4 Traitements - Economie

Global Cancer Angiogenesis Inhibitor Market Research Report 2016 [ReportsnReports]

5.6 ESMO

Exelixis-discovered Compounds To Be Featured in 15 Presentations at the ESMO 2016 Congress [Exelixis]

6.1 Observation

New data on cancer treatment to help improve care [Cancer Research UK]

Chemotherapy mortality study could help improve cancer care in England [The Guardian]

6.9 Controverses

Woman who withheld son's cancer drugs out of pity admits attempted murder [The Guardian]