Onco Actu du 12 septembre 2016

	1. Biologie
Cancer cells may ‘piggyback’ on blood platelets to spread [Cancer Research UK] The spread – or metastasis – of cancer cells to other areas of the body is the leading cause of cancer-related death. And the findings in mice, from the French Blood Establishment, suggest that targeting particular molecules on platelets may help stop this process.
	4. Dépistage, diagnostic et pronostic
A Map To Help Cancer Doctors Find Their Way [NPR] A mapping program, called PiCnIc for short, aims to help physicians in staying a step ahead of cancer and preparing long-term treatment plans with fewer elements of surprise.
	4.12 Biopsies liquides
Case for Liquid Biopsies Builds in Advanced Lung Cancer [Penn Medicine] About half of the 102 patients in this study did not have sequenceable biopsy tissue, so researchers relied on blood tests to detect mutations.
	5. Traitements
Deriving Drug Discovery Value from Large-Scale Genetic Bioresources: Proceedings of a Workshop (2016) [NAP] Participants at the workshop explored the current landscape of genomics-enabled drug discovery activities in industry, academia, and government; examined enabling partnerships and business models; and considered gaps and best practices for collecting population data for the purpose of improving the drug discovery process.
Pancreatic Cancer Progress? Maybe [In the Pipeline] The predefined metastatic group actually did show what could be a significant effect, and that’s unfortunately cancelled out by the localized tumor patients, who actually died more quickly in the treatment group. There have been some headlines about this study, but (perhaps understandably) none of them mention that last part.
	5.9 AACR
Ovarian Cancer Research Symposium Set for Seattle [Cancer Research Catalyst] In an era of tremendous progress against many types of cancer, ovarian cancer remains difficult to diagnose and treat.
	6. Lutte contre les cancers
Q&A: Kathy Hudson [Nature] The US Precision Medicine Initiative (PMI) aims to gather health data on at least one million volunteers. Kathy Hudson, deputy director for science, outreach and policy at the US National Institutes of Health (NIH), led its creation, and spoke to Nature about the challenges she faced.
Technology: Read the instructions [Nature] Remarkable progress in sequencing technologies and data handling is making personalized genome analysis an increasingly common feature of health care.
Perspective: The precision-oncology illusion [Nature] Precision oncology has not been shown to work, and perhaps it never will, says Vinay Prasad.
Pharmacogenetics: The right drug for you [Nature] Personalized prescribing is gaining momentum, but is there enough evidence for it to become standard clinical practice?
Precision medicine [Nature] We are pleased to acknowledge the financial support of Illumina, Inc. in producing this Outlook. As always, Nature has sole responsibility for all editorial content.
	6.1 Observation
Childhood cancer survivors living longer, cancer-free [Reuters] To investigate long-term health outcomes for childhood cancer survivors, the researchers analyzed data on 34,489 survivors of childhood cancer diagnosed between 1940 and 2006.
	6.10 Politiques
Richard Smith: The “micro-macro problem” and the difficulty of using evidence to make policy [BMJ] I’ve heard many talks on evidence in policy making, and the conclusion is always that evidence plays a part but that it’s small and that the link with what policies are adopted is often obscure. Making policy is fundamentally different from treating patients.
	6.10.1 Politiques (USA)
Blue Ribbon Panel Report: The Power of the Cancer Community Coming Together [NCI] I am confident that the cancer community will build upon this effort and seize this unprecedented opportunity to accelerate progress against cancer.
The Cancer Moonshot: Hype versus reality [Science-Based Medicine] Unfortunately, the whole concept of a “moonshot,” while well-suited for focused engineering problems such as landing a human being on the moon, is poorly suited to a problem like “eliminating cancer as we know it,” which, by the way, is a poorly defined goal.
'Moonshot' initiative to fight cancer urged to include survivors' lives [The Guardian] Some advocates say research focus is promising but recommendations do not address survivorship, which affects things such as mental and financial health.
	6.8 Communication
Cancer Survivorship Is On The Rise -- And That's Both Good News And Bad [Forbes] The Stand Up to Cancer (SU2C) telethon is tonight, and the hour-long TV event promises to offer a mix of inspiring cancer survivors and celebrities like Jon Hamm and Kristen Wiig hailing the accomplishments of the eight-year-old fundraising outfit, which has hauled in $370 million for oncology research so far.
How we made a musical about cancer [The Guardian] It starts as a musical, but it ends up being just a lot of people sitting in a room talking about death.
	6.9 Controverses
Project Seeks to Improve Image of Animal Research [The Scientist] A new initiative in Germany aims to increase the public’s comfort with animal-based science; US government holds workshop on nonhuman primate research.