mardi 23 août 2016

Onco Actu du 23 août 2016

1. Biologie

‘Surprising’ imbalance in cell growth could help oesophageal cancers form [Cancer Research UK]

2.8 Etiologie - Contraceptifs, THS

HRT triples the risk of breast cancer, biggest ever study shows [The Telegraph]

Combined HRT could increase breast cancer risk by nearly 300% [The Guardian]

3.2 Prévention - Obésité

3 reasons why the Government’s children’s obesity plan will fail children [Cancer Research UK]

4. Dépistage, diagnostic et pronostic

Gene scanning 'could improve screening for oesophageal cancer' [NHS Choices]

4.11 Dép., diag. & prono. - Ovaire

All women with ovarian cancer should be offered genetic testing – so why aren’t they? [Cancer Research UK]

Tests without Proven Benefit Still Used for Ovarian Cancer Surveillance [National Cancer Institute]

4.2 Dép., diag. & prono. - Génome

Genetic Testing: Does Knowing Risk of Disease Make a Difference? [Science-Based Medicine]

4.9 Dép., diag. & prono. - Sein

Women with dense breasts may need annual mammograms [Reuters]

5. Traitements

Expecting the Worst Increases Side-Effects in Breast Cancer Patients Receiving Adjuvant Hormone Therapy [ESMO]

Nanoparticle Counteracts Chemotherapy Resistance [National Cancer Institute]

5.10 Traitements - Essais

Many clinical trials’ findings never get published. Here’s why that’s bad [STAT]

5.12.2 Immunothérapies - CAR-T

CAR T Cell Therapy for Diffuse Large B Cell Lymphoma Included in EMA’s PRIority MEdicines Scheme [ESMO]

Evolving Field of CAR-T-Cell Therapy [ESMO]

5.2 Pharma

Janssen Submits Application to U.S. FDA to Expand Indication for Daratumumab (DARZALEX®) [Johnson & Johnson]

A biotech firm, on the brink of ruin, resurrects itself via man — and microbe [STAT]

5.2.2 Pharma - Fusions & Acquisitions

Sanofi's Hostility Backfires [Bloomberg]

Pfizer boosts cancer drug roster with $14 billion Medivation deal [Reuters]

Pfizer Buys Medivation [In the Pipeline]

Pfizer to buy cancer drug company Medivation in $14bn deal [The Guardian]

5.2.3 Pharma - économie

With New Name and $86M, Tioma To Explore Anti-CD47 Cancer Therapy [Xconomy]

5.3 Traitements - FDA, EMA,...

Addressing challenges of innovative cancer immunotherapy medicines [EMA]

5.4 Traitements - Economie

NICE rejects Bayer’s Nexavar for liver cancer [PharmaTimes]

NICE recommends crizotinib for lung cancer [NICE]

With $14 Billion Purchase, Pfizer Signals That Cancer Drug Prices Will Remain High [Forbes]

6. Lutte contre les cancers

Survey shows broad support for national precision medicine study [NIH]

Sometimes Bold Predictions Do Come True: The Lesson Of Chronic Myeloid Leukemia [Dr. Len's Blog]

6.1 Observation

Cancer survivors’ sex lives as good as others their age [Cancer Research UK]

9/11 and Cancer: Behind the Headlines [ACS]

Epidemic or Thyroid Cancer Over-diagnosis? [American Thyroid Association]

Got a Thyroid Tumor? Most Should Be Left Alone. [NY Times]

Social class may influence multiple myeloma survival [Reuters]

6.10.1 Politiques (USA)

Clinton endorses Biden’s cancer program, says she’ll ‘take up the charge’ [STAT]

6.11 Patients

Jimmy Carter thought he had just weeks to live during cancer fight [STAT]

6.6 Publications

ORCID: We won't be sold [ORCID]

Five more retractions for researcher who sued PubPeer commenters brings tally to 18 [Retraction Watch]

6.7.1 Bioinformatique

Watson goes to Asia: Hospitals use supercomputer for cancer treatment [STAT]

6.7.2 Applis

Apple's Latest Acquisition Could Give Its Health Platform an Edge on Alphabet's [The Street]

6.8 Communication

New American Cancer Society Breast Cancer Book Offers Newly Diagnosed Hope [ACS]

6.9 Controverses

Too many treatment guidelines are written by experts with financial conflicts, study finds [STAT]

What Is Precision Medicine? [NeuroLogica Blog]

In CRISPR Fight, Co-Inventor Says Broad Institute Misled Patent Office [MIT Technology Review]

Clinical trials doctors claim they own patients' data, want others to pay for access [Genomics, Medicine, and Pseudoscience]