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2. Etiologie
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Why Does Cancer Risk Increase As We Get Older? [Dana-Farber Cancer Institute]
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One
view is that cancer develops in older people simply because of their
prolonged exposure to carcinogens such as sunlight, radiation,
environmental chemicals, and substances in the food we eat. Mutations
also occur as a result of random errors when a cell’s DNA is copied
before it divides. As a result, our cells accumulate more mutations the
longer we live.
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3.3 Prévention - Vaccins
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A new jab to prevent cancer [BMJ Blogs]
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The
9-valent vaccine, as the name suggests, protects against nine types of
HPV—that means protection against an extra five HPV types compared with
the other two vaccines. These nine HPV types cause up to 90% of cervical
cancers, so an additional 10 in every 100 cervical cancers could be
prevented.
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3.8 Prévention - Alimentation
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Broccoli compounds may help combat chronic diseases [NHS Choices]
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"Eating
broccoli could lower your risk of having coronary heart disease, type 2
diabetes and several types of cancer, a new study suggests," the Daily
Mail reports.
But there is little hard evidence to back up this claim – the study it
reports on involved plants, not humans.
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4.2 Dép., diag. & prono. - Génome
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5. Traitements
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Reality check from Eric Lander: Majority of cancer cures will take decades [STAT]
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Eric
Lander, who co-chairs the President’s Council of Science and
Technology, hopes the administration’s recently announced cancer
“moonshot,” led by Vice President Joe Biden, will help shorten this time
frame. “It’s not going to be all done in 10 years, but if we get it
done in 40 years, I’m not going to be embarrassed.”
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5.12 Immunothérapies
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5.2 Pharma
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Astellas suspended from UK pharma trade group for ‘deception on a grand scale’ [STAT]
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The
suspension had its roots in a meeting that the Astellas division in the
UK held in Milan in February 2014 for more than 100 physicians. The
company billed the gathering as an educational event to obtain advice
about prostate cancer when, in fact, it was more of a promotional stunt
designed to woo doctors who were targeted to become high prescribers for
Xtandi.
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5.2.2 Pharma - Fusions & Acquisitions
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5.2.3 Pharma - économie
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Pharma's Cold Brexit Comfort [Bloomberg]
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The
actual sales impact of Brexit may be limited for pharma and biotech, at
least compared to other industries. With a few exceptions, many
drugmakers get the most significant part of their revenue from the U.S.
The U.K. is only a small hunk of ex-U.S. revenue, and its patients pay
substantially less for drugs than those in many other countries.
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5.3 Traitements - FDA, EMA,...
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Post-Brexit, will the European Medicines Agency be homeless? [STAT]
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Bates
estimated that the UK drug agency actually does about a third of the
work underlying reviews by the EMA. The MHRA will have to fortify its
internal drug review process, to make up for the absence of the EMA’s
function. And, in turn, Bates said the European agency may lose out on
benefitting from the MHRA’s strengths in patient safety regulation.
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5.3.4 Traitements - AMM (FDA, EMA)
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Arzerra [EMA]
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On
23 June 2016, the Committee for Medicinal Products for Human Use (CHMP)
adopted a negative opinion, recommending the refusal of a change to the
marketing authorisation for the medicinal product Arzerra (ofatumumab).
The change concerned an extension of indication to add maintenance
treatment for adults with chronic lymphocytic leukaemia.
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6. Lutte contre les cancers
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ESMO Launches First Leaders Generation Programme [ESMO]
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The
two-part programme** – which is being led by some of the most
experienced and eminent oncologists in Europe – will give participants
the knowledge and skills they need to thrive as leaders in the
increasingly specialised and fast-changing field of oncology.
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6.10 Politiques
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EU referendum: UK science wakes up to new future [BBC News]
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Britain's
science sector has done increasingly well out of the EU in recent
years, receiving €8.8bn in research funding in 2007-2013 versus the
€5.4bn it paid in over the same period. And UK-based scientists have won
about a fifth of all the grants, in terms of value, from the top-tier
programmes run by the European Research Council.
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