Onco Actu du 23 juin 2016

	2. Etiologie
Infectious shellfish cancers may jump across species [Nature News & Comment] The parasitic tumours showed up in clams, mussels and other bivalves.
The Contagious Cancer That Jumped Between Species [The Atlantic] It has spread from one clam species to another, and is one of now eight transmissible tumors.
Cancer Is Contagious Among Clams. What About Us? [NY Times] “We were always thinking there would be more contagious cancer out there, but we didn’t know where they would be discovered,” said Elizabeth P. Murchison, a cancer biologist at the University of Cambridge who was not involved in the new study.
	3. Prévention
Adherence to Cancer Prevention Guidelines May Reduce Risk [AACR] Review of multiple studies shows consistent reductions for overall incidence and mortality.
	4. Dépistage, diagnostic et pronostic
Microsoft, Median team up to build IT-enabled early cancer detection system [FierceBiotech] That approach to processing, Ibiopsy, is the latest attempt by Median to extract early, accurate biomarkers of disease from medical images. Median already possesses algorithms to automate the detection, quantification and tracking of lesions and other abnormalities in medical images.
IBM Watson Health Launches Imaging Effort for Cancer, Other Diseases [Xconomy] Watson Health is pushing the idea of “cognitive imaging”—using computers to understand and draw clinical insights from images and other medical data—to try to help doctors provide better care at lower cost than the status quo.
High-tech scans spare lymphoma patients intensive chemo [Cancer Research UK] Doctors – funded by Cancer Research UK and international partners in Europe and Australasia – used positron emission tomography (PET) to scan more than 1200 patients with advanced Hodgkin lymphoma after they had been given two cycles of standard chemotherapy.
	4.2 Dép., diag. & prono. - Génome
China’s bid to be a DNA superpower [Nature News & Comment] First China conquered DNA sequencing. Now it wants to dominate precision medicine too.
	5.12 Immunothérapies
Atlas, Novartis Put $27M Into IFM to Battle Cancer, Autoimmune Diseases [Xconomy] There is no shortage of companies out there trying to tweak our immune systems in one way or another to treat diseases like cancer. Today, IFM Therapeutics, a new startup seeded by Boston firm Atlas Venture, has joined the fray.
I/O: The Strategic Supernova In Cancer Today [Life Sci VC] This flood of I/O projects presents a large number of important strategic implications; it’s very hard to do justice to them all with one blog post, but here are four top of mind thoughts.
	5.12.2 Immunothérapies - CAR-T
New CAR T Cell Therapy Using Double Target Aimed at Solid Tumors [Penn Medicine] Penn Medicine Pre-Clinical Study Shows How Antibody, Carbohydrate Combination Could Apply to Range of Cancer Types.
	5.2 Pharma
Infinity's Sad RUD [Omics! Omics!] I ran into the head of biology at a networking event just after the trial halt, and he was still in complete shock. Unsurprising, as the pre-clinical data was excellent, including engineered mouse models.
	5.2.1 Pharma - Partenariats
Celgene backs four NCI Cancer Centers with $50M to create research consortium [FierceBiotech] The institutions include The Abramson Cancer Center at the University of Pennsylvania, The Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, and The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.
	5.2.3 Pharma - économie
Russian drug maker says Roche tried to ‘destroy’ its ability to sell biosimilars [STAT] Among the steps Roche took to undercut Biocad was to deliberately drop prices for three cancer medicines — Avastin, Herceptin, and Rituxan/MabThera — in Russia, where the company said it sells biosimilar versions, according to a lawsuit filed two weeks ago in federal court in New York.
	5.3 Traitements - FDA, EMA,...
EMA and FDA reinforce collaboration on patient engagement [EMA] New working group established to exchange best practices.
	5.9 AACR
How Can Engineering Help Fight Cancer? AACR to Host Special Conference on Engineering and Physical Sciences [CANCER RESEARCH Catalyst] Experts in physical sciences and engineering have a lot to offer and we hope to be a part of this important initiative. Maybe President Obama can talk to Vice President Biden about our work.
	6.6 Publications
JAMA Forum: Undue Influence: The P Value in Scientific Publishing and Health Policy [JAMA] The P value doesn’t measure a probability. It doesn’t tell us the anything about how likely a result could have occurred by chance alone (another misinterpretation). It also doesn’t set a bar for whether we should take something seriously.
JAMA: No plan to pull elephant-cancer risk paper after PETA protest (Retraction Watch] People for the Ethical Treatment of Animals (PETA) recently protested the 2015 paper, which found that higher levels of a tumor suppressor gene could explain why elephants have a lower risk of cancer.