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1. Biologie
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Predictive Genomics [HMS]
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Combining
two emerging, large-scale technologies for the first time—multiplexed
mass spectrometry and a mouse population with a high level of natural
genetic diversity—researchers at Harvard Medical School and The Jackson
Laboratory can now crack an outstanding question in biology and
medicine: How do genetic variants affect protein levels?
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2.11 Etiologie - Alimentation
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Why It's So Hard to Determine If Food and Drinks Cause Cancer [Motherboard]
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“Humans
are incredibly complicated organisms that live in incredibly
complicated environments and we make lots of different decisions
throughout the day related to our health and some of them we’re not even
aware of,” Caulfield told me. “So in order to isolate the effect or
impact of one compound, or one food, it can be really difficult. There
are so many variables at play.”
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WHO Agency Downgrades Coffee’s Cancer Link [ACS]
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The
news that coffee is being downgraded from “possible carcinogen” to
“unclassifiable” sounds surprising, since we’re used to seeing trends go
the other way, from safe to potentially cancer-causing. But this is how
the scientific process works.
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Coffee and cancer – what does the evidence say? [Cancer Research UK]
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And
if you don’t drink coffee already? We wouldn’t suggest this news means
you need to start. The evidence is still uncertain, and if subsequent
research does reveal an effect, it’s probably small – much smaller than
any positive benefits gained from the important things, like keeping a
healthy weight or cutting down on the amount of alcohol you drink.
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Hot drinks may cause cancer, but coffee does not, says WHO [The Guardian]
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Those
who enjoy hot tea in Europe and the US probably do not need to worry,
Loomis said. “It is important to recognise that hot drinks that were
studied for the basis of this classification are perhaps a bit different
from tea or coffee as consumed [in other parts of the world] – 65C is
quite hot.”
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4.11 Dép., diag. & prono. - Ovaire
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4.5 Dép., diag. & prono. - Colorectal
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4.9 Dép., diag. & prono. - Sein
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5. Traitements
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Ultrasound Opens the Brain to Promising Drugs [MIT Techology Review]
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Carpentier,
who invented SonoCloud and founded its parent company, CarThera, says
the most surprising part was the patients’ response to the implant. “The
patients don’t feel anything when we emit ultrasound,” he says. “And
they actually don’t complain about it. It was set up in the protocol to
remove it after six months, but patients don’t want to remove it.”
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5.12 Immunothérapies
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5.2.3 Pharma - économie
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5.3.4 Traitements - AMM (FDA, EMA)
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5.5 ASCO
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6.7 DMP, Big Data & applis
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