vendredi 10 juin 2016

Onco Actu du 10 juin 2016

1.1 Biologie - Gènes

Acute myeloid leukaemia is 11 different diseases [Cancer Research UK]

3.1.1 Tabac - e-cigs

Electronic Cigarette Use Among Working Adults — United States, 2014 [MMWR]

3.5 Prévention - UV

12 sun safety myths debunked [Cancer Research UK]

4.9 Dép., diag. & prono. - Sein

Intrinsic molecular subtyping enables fine-tuned prognosis and prediction of tumor behavior in patients with advanced breast cancer [Vall d'Hebron Institute Oncology]

5.12 Immunothérapies

A Scientist's Dream Fulfilled: Harnessing The Immune System To Fight Cancer [NPR]

June is Cancer Immunotherapy Month [CANCER RESEARCH Catalyst]

5.2 Pharma

Data in The Lancet Show Olaratumab Plus Doxorubicin Offered 11.8-Month Increase in Overall Survival in Patients with Advanced Soft Tissue Sarcoma, as Reported by Lilly and Memorial Sloan Kettering Researchers [Lilly]

5.2.1 Pharma - Partenariats

Pierre Fabre, Merck KGaA team up for MEK-BRAF-Erbitux cancer combo trial [FierceBiotech]

5.2.3 Pharma - économie

Pfizer just raised drug prices by an average of nearly 9 percent [STAT]

5.3 Traitements - FDA, EMA,...

Researchers Propose Framework to Validate Surrogate Endpoints [RAPS]

Single, central platform now mandatory for all periodic safety update reports [EMA]

5.5.1 ASCO (général)

Notes from ASCO 2016 [Open Reading Frame]

5.5.8 ASCO (poumon)

Lung Cancer Highlights from ASCO [Lung Cancer Alliance]

The Surprising Degree By Which MoovCare, A Web App, Helps Cancer Patients Live Longer [Forbes]

5.9.3 EHA

New Data on Bristol-Myers Squibb’s Opdivo (nivolumab) Indicate Benefit in Heavily Pre-Treated Classical Hodgkin Lymphoma Patients in Phase 2, Single-Arm Pivotal Trial [BMS]

Bristol-Myers Squibb to Present New Data Demonstrating Continued Research Expansion and Immuno-Oncology Advancements Across Multiple Blood Cancers at the 21st Congress of the European Hematology Association [BMS]

BLINCYTO Blinatumomab Improved Overall Survival In Patients With BCell Precursor Acute Lymphoblastic Leukemia [Amgen]

Restoring Effective Anti-Tumor Response in Hodgkin Lymphoma with Nivolumab [EHA]

Stopping Tyrosine Kinase Inhibitors in a Very Large Cohort of European Chronic Myeloid Leukemia Patients: Results of the EURO-SKI Trial [EHA]

Immunotherapy delivered by Blinatumomab improves survival in acute lymphoblastic leukaemia patients [EHA]

The root of evil: pre-leukemic clones that survive chemotherapy are linked to a higher risk of leukemia recurrence [EHA]

Daratumumab Shows Remarkable Benefit in Relapsed or Refractory Multiple Myeloma in the POLLUX Study [EHA]

6.1 Observation

Prescription habits predict compliance with breast cancer pills [Reuters]

6.10 Politiques

Stanford Medicine X Leads Precision Medicine Workshop At The White House [Scope Blog]

Colombia plans to unilaterally lower the cost of a Novartis cancer drug [STAT]

Colombia to set new price for Novartis cancer drug: minister [Reuters]

6.7 DMP, Big Data & applis

Using big data, scientists discover biomarkers that could help give cancer patients better survival estimates [UCLA]