jeudi 28 avril 2016

Onco Actu du 28 avril 2016

1. Biologie

The quiet revolutionary: How the co-discovery of CRISPR explosively changed Emmanuelle Charpentier’s life [Nature News & Comment]

2.11 Etiologie - Alimentation

Does canned food cause cancer? [The Telegraph]

3.1 Tabac

Doctors warn of big tobacco firms entering e-cigarette market [The Guardian]

Reducing the harm of tobacco, could e-cigarettes be part of the solution? [Cancer Research UK]

UK doctors urge wide promotion of e-cigs to help smokers quit [Reuters]

E-cigarettes should be offered to smokers, say doctors [BBC News]

Smokers Urged to Switch to E-Cigarettes by British Medical Group [NY Times]

Promote e-cigarettes widely as substitute for smoking says new RCP report [Royal College of Physicians]

U.K. Report Advocates E-Cigarettes as Tobacco Substitute [Wall Street Journal]

5. Traitements

Tackling Cancers Of The Immune System With Customized “peptibodies” [Scope Blog]

5.10 Traitements - Essais

Phase 3 Trial Results for First Oral Proteasome Inhibitor NINLARO (ixazomib) Published in The New England Journal of Medicine [Takeda]

5.12 Immunothérapies

Tumor burden, not cancer per cell antigen density or T cell receptor affinity, determine immunotherapy outcome [NIHilist's Immunology]

5.2.2 Pharma - Fusions & Acquisitions

Sanofi offers $9.3B for Medivation--but the biotech isn’t biting [FierceBiotech]

AbbVie to Expand Oncology Presence Through Acquisition of Stemcentrx and its Novel, Late-Stage Rova-T Compound for Small Cell Lung Cancer [AbbVie]

Sanofi Offers to Acquire Medivation for $ 52.50 Per Share in Cash [Sanofi]

5.2.3 Pharma - économie

What’s a billionaire biotech CEO worth? Soon-Shiong’s price is $148M [FierceBiotech]

Bristol-Myers Squibb Reports First Quarter Financial Results [BMS]

UBS, MPM team up on $471 million cancer fund to speed drug development [Reuters]

5.3 Traitements - FDA, EMA,...

Involving general practitioners in regulatory decisions on medicines [EMA]

5.3.4 Traitements - AMM (FDA, EMA)

Servier's Lonsurf approved in Europe for colorectal cancer [PharmaTimes]

5.4 Traitements - Economie

Small company offers Medicare cheap version of pricey cancer drug [STAT]

5.9.5 AACR - T-cell immunothérapies

AACR Annual Meeting 2016: Can a Universal Adaptor Overcome CAR T-cell Immunotherapy Limitations? [CANCER RESEARCH Catalyst]

6.1 Observation

Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk, Penn Study Suggests [UPenn]

6.10 Politiques

Biden time [Nature News & Commrnt]

6.11 Patients

'My tattoo art helps women feel beautiful after breast cancer' [The Guardian]

6.9 Controverses

What (if anything) does “natural” mean? [Science-Based Medicine]

5 Tips For Avoiding P-Value Potholes [Absolutely Maybe]