jeudi 21 avril 2016

Onco Actu du 21 avril 2016

1. Biologie

First computer program developed to detect DNA mutations in single cancer cells [MD Anderson]

Dirty room-mates make lab mice more useful [Nature News & Comment]

2.11 Etiologie - Alimentation

Several lifestyle factors linked to stomach cancer for first time [World Cancer Research Fund International]

Eating two rashers of bacon a day increases risk of stomach cancer [The Telegraph]

3.4.1 Chimioprévention - aspirine

Aspirin Use May Help Prevent Bile Duct Cancer [Mayo Clinic]

4.12 Biopsies liquides

What Is a Liquid Biopsy? [Dana-Farber Cancer Institute]

5. Traitements

Daily aspirin boosts survival in cancer patients, study shows [The Telegraph]

5.12 Immunothérapies

Treatments for cancers and Alzheimer's on the verge of a breakthrough [The Guardian]

5.2.1 Pharma - Partenariats

AbbVie, argenx sign $685M preclinical immuno-oncology deal [FierceBiotech]

AbbVie gets option on early Argenx cancer drug for $40 million [Reuters]

5.2.2 Pharma - Fusions & Acquisitions

Pharma and biotech companies: Don’t just merge, innovate [STAT]

5.2.3 Pharma - économie

Novartis delivered solid Q1 despite Gleevec loss of exclusivity; investing behind new launches for long-term growth [Novartis]

Ignoring Criticism, Drug Companies Still Raising Prices, Making More Money [TheStreet]

5.3 Traitements - FDA, EMA,...

Califf: FDA can’t isolate itself from industry, despite ‘touchy’ issues [STAT]

5.5 ASCO

Exelixis-Discovered Compounds to Be Featured in 18 Presentations at 2016 ASCO Annual Meeting [Exelixis]

5.9 AACR

Vice President Biden and Dr. Jill Biden Address the Cancer Research Community at the AACR Annual Meeting 2016 [AACR]

What the cancer 'moonshot' needs to fix [Politicio]

A Shared Commitment to the Cancer Moonshot [National Cancer Institute]

Speaking of Cancer Research [The Scientist]

Biden to cancer researchers: How can we move faster on this? [Washington Post]

Biden urges cancer researchers to work together toward ‘moonshot’ goals [STAT]

5.9.1 AACR - sein

Preclinical Data Presented at American Association for Cancer Research (AACR) Annual Meeting Demonstrate Enhanced Therapeutic Benefit of Combining a PS-Targeting Antibody With Anti-PD-1 Therapy in Models of Triple Negative Breast Cancer (TNBC) [Peregrine]

5.9.5 AACR - T-cell immunothérapies

Juno’s Investigational CAR T Cell Product Candidates JCAR018 and JTCR016 Demonstrate Encouraging Clinical Responses in Patients with B-Cell and Mesothelioma Cancers [Juno Therapeutics]

5.9.7 AACR - divers

AACR Annual Meeting 2016: A Microdevice That Has the Potential to Find the Right Cancer Treatment for a Patient [CANCER RESEARCH Catalyst]

Mouth Microbes and Pancreatic Cancer [The Scientist]

5.9.9 AACR - immunothérapies

Opdivo has a brief opportunity to CheckMate other immunotherapies in head and neck cancer [The OBR Blog]

6.7 DMP, Big Data & applis

Five ways we can harness the power of Big Data to transform cancer research and treatment [The Institute of Cancer Research]

6.9 Controverses

NIH suspends clinical trials after contamination risk discovered [Nature News & Comment]