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1. Biologie
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2.11 Etiologie - Alimentation
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3.1 Tabac
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4. Dépistage, diagnostic et pronostic
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It’s Not Cancer: Doctors Reclassify a Thyroid Tumor [NY Times]
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As
a result, they have officially downgraded the condition, and thousands
of patients will be spared removal of their thyroid, treatment with
radioactive iodine and regular checkups for the rest of their lives, all
to protect against a tumor that was never a threat.
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5. Traitements
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Rerouting Cancer [Caltech]
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In
mice, Heath and his team tested seven therapies or therapy combinations
that they predicted would—or would not—halt resistance development. The
four that they predicted would not work were, indeed, ineffectual; the
three they thought would work, did.
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5.10 Traitements - Essais
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Patient advocates urge action on clinical trials reporting [STAT]
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“Patient
advocacy groups across the US are very concerned with the disregard for
human life, patient safety, transparency, and accountability the NIH,
and the FDA, have shown by not enforcing timely reporting of” clinical
trial results, the advocates wrote in a January letter to NIH director
Dr. Francis Collins.
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5.12 Immunothérapies
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Sleeping immune cells in tumours can be 'woken up' to fight cancer [The Telegraph]
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The
treatment would work by taking a biopsy of a tumour and then identify
immune cells that are already inside. Those cells are likely to me most
effective as the fact that they are in the tumour suggests they were
trying to attack it before they got switched off. Scientists then use a
genetic editing technique called TALEN to remove the ‘off switch’. The
edited immune cells are then multiplied in a lab and replaced back in
the body.
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5.12.3 Immunothérapies-combinaisons
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Immuno-Oncology Combinations [Citeline]
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As
a follow-up to the last webinar on immuno-oncology combinations,
Citeline has produced this infographic to highlight some additional
aspects of these combinations that were not covered in the webinar.
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5.2 Pharma
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5.3 Traitements - FDA, EMA,...
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5.3.4 Traitements - AMM (FDA, EMA)
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5.6.4 ESMO - Poumon
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5.9 AACR
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6. Lutte contre les cancers
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ESMO Welcomes Final Version of European Data Protection Regulation [ESMO]
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“The
inclusion of a one-time consent for retrospective research on clinical
data and biological tissues is crucial because it means the oldest form
of medical research – going back to patient records to analyse and
correlate data – can continue to make a contribution today, to solving
the challenges of tomorrow.”
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6.1 Observation
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6.10 Politiques
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6.11 Patients
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6.3 Associations
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6.6 Publications
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Why our peer review system is a toothless watchdog [STAT]
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“In
reality, however, peer review is ineffective, largely a lottery,
anti-innovatory, slow, expensive, wasteful of scientific time,
inefficient, easily abused, prone to bias, unable to detect fraud and
irrelevant.”
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Biology Papers Are Currency [Mike the Mad Biologist]
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To
put this simply, do you know the difference between a couple of papers
in BiorXiv and in journals? $250,000 per year in direct costs from NIH,
and somewhere between $75,000 and $125,000 in indirect costs.
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