mardi 12 avril 2016

Onco Actu du 12 avril 2016

1. Biologie

Macrophages surrounding lymph nodes block the progression of melanoma, other cancers [Massachusetts General Hospital]

1.1 Biologie - Gènes

Mystery factors protect lucky few from severe genetic disorders [Nature News & Comment]

‘Buffer genes’ may protect these 13 people from rare genetic diseases [Science]

Thirteen Anonymous Genetic Superheroes Walk Among Us—Or Do They? [The Atlantic]

Scientists search for 13 people to solve genetic mutation mystery [The Guardian]

Search for New Medical Treatments Zeroes in on Genetic Superheroes [MIT Technology Meview]

3.3 Prévention - Vaccins

ASCO Urges Aggressive Efforts to Increase HPV Vaccination and Prevent Cancer [ASCO]

3.4.1 Chimioprévention - aspirine

Experts debate: Do healthy people need an aspirin a day? [STAT]

4.9 Dép., diag. & prono. - Sein

BRCAness – going beyond the BRCA genes [The Institute of Cancer Research]

5. Traitements

Nanoparticle generator targets metastatic breast cancer [National Cancer Institute]

A Simple Tool to Ease Cancer's Side Effects [Wall Street Journal]

5.10 Traitements - Essais

Clinical Trials Need More Subjects [Wall Street Journal]

5.12.2 Immunothérapies - CAR-T

Celgene pays Juno $50M as it drives deeper into a $1B CAR-T collaboration [FierceBiotech]

5.2.3 Pharma - économie

The one drug pricing idea Hillary Clinton and PhRMA can agree on [STAT]

5.3.4 Traitements - AMM (FDA, EMA)

Roche announces FDA grants Venclexta(venetoclax) accelerated approval for people with hard-to-treat type of chronic lymphocytic leukemia [Roche]

FDA approves new drug for chronic lymphocytic leukemia in patients with a specific chromosomal abnormality [FDA]

AbbVie/Roche drug gets U.S. approval for a rare type of leukemia [Reuters]

5.4 Traitements - Economie

This nonprofit is playing a valuable role in framing the drug price discussion [STAT]

6. Lutte contre les cancers

New public repository of patient-derived cancer models aims to improve drug testing [Dana-Farber Cancer Institute]

Cancer Tissue Repository Launched (The Scientist]

#Cancer: Researchers Are Conducting Huge Studies Using Twitter, Facebook [Fast Company]

6.1 Observation

Hormone Therapy for Prostate Cancer Tied to Depression [NY Times]

Marriage is good for cancer patients [Reuters]

6.10 Politiques

Precision medicine helped him beat cancer. Now he’s leading Obama’s initiative [STAT]

Selection of Eric Dishman as Director of the Precision Medicine Initiative Cohort Program [National Institutes of Health]

6.5 Médecines alternatives

Functional medicine: The ultimate misnomer in the world of integrative medicine [Science-Based Medicine]

6.6 Publications

Paper on GI cancers linked to AIDS pulled for errors that upped tumor incidence [Retraction Watch]

So long to the silos [Nature Biotechnology]