Onco Actu du 9 mars 2016

	2. Etiologie
Talc and ovarian cancer: what the most recent evidence shows [NHS Choices] However, these analyses were based on much smaller sample sizes. For example, the 2.33 risk increase for premenopausal women using talc for more than 24 years involved just 41 cases and 21 controls.
	2.11 Etiologie - Alimentation
'Carbs linked to lung cancer,' study finds [NHS Choices] Despite the media headlines, this study does not provide evidence that suggests carbohydrates are as much of a risk factor for lung cancer as smoking. Smoking remains the most well-established risk factor for lung cancer.
	3.1 Tabac
Smoking could cause disease in more than 1.3 million over the next 20 years [Cancer Research UK] If recent trends were to continue, Cancer Research UK and the UK Health Forum calculate that this shocking total – equivalent to a city the size of Sheffield – would include 580,600 cases of cancer.
Nagging smokers does not help them quit, say researchers [The Telegraph] Simple activities such as helping with tasks like shopping or looking after children make it more likely smokers will cut down on cigarettes, study finds.
	3.3 Prévention - Vaccins
Sanofi and Merck pull the plug on European vaccines venture [Reuters] Sanofi Pasteur MSD is a major supplier of flu vaccines in Europe and also distributes Gardasil to protect against cervical cancer.
	3.4 Chimioprévention
10p pills could protect against breast cancer risks [The Telegraph] “The findings suggest that treating diabetes with diet or pills (metformin) could decrease breast density, while insulin could increase it."
	4.10 Dép., diag. & prono. - Poumon
New guidelines recommend CT scans for lung cancer in long-time smokers [The Globe and Mail] The Canadian Task Force on Preventive Health Care says adults from the ages of 55 to 74 with a history of significant tobacco use should be tested for signs of lung cancer annually over three consecutive years using the sensitive radiological imaging device.
	4.2 Dép., diag. & prono. - Génome
Massive amount of cancer patient data released for free [STAT] The information posted on Tuesday is anonymized, and comes from individuals who took Ambry’s genetic tests and provided consent.
Genetic Test Firm to Put Customers’ Data in Public Domain [NY Times] In an unusual move, a leading genetic testing company is putting genetic information from the people it has tested into the public domain, a move the company says could make a large trove of data available to researchers looking for genes linked to various diseases.
	5. Traitements
DNA Barcodes Could Streamline Search for New Drugs to Combat Cancer [NIH Director's Blog] With PRISM, it’s now feasible to screen entire small molecule libraries across large panels of cancer cell lines. The approach might also be put to use for optimizing drug candidates or for discovering new uses for cancer drugs that have already been FDA approved.
	5.2.1 Pharma - Partenariats
Ensemble Quietly Amasses Cancer Drug Pipeline, Scouts for New Deals [Xconomy] Ensemble is best known for developing a library of synthetic macrocycles—molecules intended to combine the properties of small-molecule drugs and antibodies to access tough-to-reach biological targets—and using it to land industry partnerships with the likes of Alexion Pharmaceuticals, Pfizer, and Bristol-Myers Squibb.
Ipsen and PeptiMimesis announce a research partnership in oncology [Ipsen] Ipsen will combine its expertise in peptide design and development with PeptiMimesis knowledge in the identification of transmembrane peptides and intracellular signaling.
	5.3 Traitements - FDA, EMA,...
What Ted Cruz Gets Wrong About The FDA: Tough Regulation Can Spark Innovation [Forbes] The problem is that a regulator like FDA doesn’t need to be lax or tough. It just needs to be right. And the best way to do that is to base decision-making on science.
	5.4 Traitements - Economie
China signals price cuts for cancer drugs, imports [Reuters] China's drive to lower the price of drugs is one of the main challenges facing drug firms in the world's second-largest medicine market, where growth has slowed markedly over the past couple of years.
	6. Lutte contre les cancers
You’ve never heard of the powerful doctors making decisions about your health [Washington Post] That authority is “a double-edged sword,” said Ned Calonge, who led the task force in 2010. “On one side, you’re a scientist and you want to make sure your work has impact. But on the other side, this direct link to an economic outcome puts a pressure on your decision-making that I feel is not positive.”
	6.10 Politiques
Hillary Clinton could put breast cancer in spotlight [STAT] Over the past 25 years, Clinton has devoted more attention to the issue of breast cancer research than any presidential candidate before her.
	6.11 Patients
Cancer gene mother chooses to have breasts and ovaries removed so she can see children grow up [The Telegraph] "The doctor talked me through my options and it was clear that both a mastectomy and hysterectomy would be needed. I didn't want to take any chances."
	6.7 DMP, Big Data & applis
How do people feel about companies accessing health data? [Wellcome Trust Blog] Overall, the findings from this research make a strong case for there being much more open, honest communication with patients about how their data is used.
	6.7.2 Applis
Health apps aren't just collecting your info. They may be selling it, too [STAT] Most health apps are completely unregulated. If you don’t want your information shared or the memory on your phone tampered with, be very careful about which apps you choose to download.
	6.9 Controverses
No, cancer is not the “best death,” and curing cancer would be anything but a waste of resources [Respectful Insolence] Unfortunately, Smith clings to a romantic view of dying from cancer that is not rooted in reality or actual experience and remains utterly tone deaf in how expresses his view. I just hope he never has the opportunity to put his romantic view of death from cancer to the test.