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1. Biologie
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2. Etiologie
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Genital talc boosts ovarian cancer risk in study [Reuters]
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Cramer
first reported a link between genital talc and ovarian cancer in 1982.
But the current study is the first to confine the association to
premenopausal women and to postmenopausal women who used hormone therapy
– which might help explain earlier contradictory results on the link
between talc and ovarian cancer, Cramer and his team write.
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2.6 Etiologie - Environnement
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3.4.1 Chimioprévention - aspirine
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4.12 Biopsies liquides
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5. Traitements
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5.12 Immunothérapies
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Cancer study identifies likely responders to immune therapy [STAT]
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The
number of neoantigens is only part of the story. This study goes beyond
previous ones in showing that when neoantigens are found throughout a
tumor rather than in some cells only, patients have the best shot at
benefitting from immunotherapy. And that’s true even if there are
relatively few neoantigens.
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This $150,000 Cancer Treatment Saved a Pharma Company [Bloomberg]
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Ono
is an anomaly among Japanese pharmaceutical companies, most of which
have struggled to find brand new medicines. Sagara credits his company’s
success with Opdivo to a gamble it took more than a decade ago in
working with some university researchers on a little known course of
treatment.
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5.12.2 Immunothérapies - CAR-T
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5.2 Pharma
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5.2.1 Pharma - Partenariats
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5.3 Traitements - FDA, EMA,...
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5.3.4 Traitements - AMM (FDA, EMA)
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FDA approves new indication for FASLODEX® (fulvestrant) [AstraZeneca]
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The
FDA approval of this new indication for FASLODEX is based on data from
the Phase III PALOMA-3 trial, which met the study’s primary endpoint of
progression-free survival (PFS). The combination of FASLODEX 500 mg and
palbociclib 125 mg resulted in a 4.9 month PFS improvement over FASLODEX
and placebo, in women with HR+ HER2- advanced or MBC whose disease had
progressed after endocrine therapy.
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