vendredi 5 février 2016

Onco Actu du 5 février 2016

1. Biologie

New clues to common and elusive KRAS cancer gene [University of Michigan Health System]

Minority of cancer cells affect the growth and metastasis of tumours [Karolinska Institutet]

Cool Videos: Spying on Cancer Cell Invasion [NIH Director's Blog]

3.8 Prévention - Alimentation

Fiber and breast cancer risk: holes in Harvard news release set stage for misleading news coverage [HealthNewsReview]

4. Dépistage, diagnostic et pronostic

Could new NHS diagnostic centres tackle vague cancer symptoms? [Cancer Research UK]

4.12 Biopsies liquides

Blood Simple? Grail's Cancer Screening Quest Faces Tough Questions [Xconomy]

Cancer Evolution – It’s in the Blood! [The Darwin Cancer Blog]

5. Traitements

Cancer cells kill off healthy neighbours [Cancer Research UK]

Keep cancer alive to stop it spreading, say scientists [The Telegraph]

5.12 Immunothérapies

ASCO Names Advance of the Year: Cancer Immunotherapy [ASCO]

Policy Issues in the Clinical Development and Use of Immunotherapy for Cancer Treatment [Institute of Medicine]

5.2 Pharma

Phase 3 Study of BLINCYTO Blinatumomab Met Primary Endpoint Of Overall Survival In Patients With BCell Precursor Acute Lymphoblastic Leukemia [Amgen]

FDA Puts Heat Biologics Bladder Cancer Trial on Partial Hold [Xconomy]

Big Pharma spending big to push patients to take their meds [STAT]

5.2.1 Pharma - Partenariats

ImmunoGen and Merck Establish Collaboration for Clinical Evaluation of Mirvetuximab Soravtansine in Combination with Keytruda® (pembrolizumab) for the Treatment of Ovarian Cancer [ImmunoGen]

5.2.3 Pharma - économie

UK lung cancer patients get early access to breakthrough BMS drug [Pharmafile]

5.3 Traitements - FDA, EMA,...

Building a Modern Generic Drug Review Process [FDA Voice]

5.4 Traitements - Economie

Cancer Drugs Fund 'should be managed better', say MPs [BBC News]

Government has no idea about Cancer Drugs Fund's impact, MPs say [The Guardian]

Even Greeks can get more medicines than Brits, Pfizer boss claims [The Guardian]

6. Lutte contre les cancers

Tackling the Global Cancer Burden: A Conversation with NCI’s Dr. Ted Trimble [National Cancer Institute]

6.1 Observation

Cancer death rates fall by almost 10 per cent in 10 years [Cancer Research UK]

Women Who Survive Breast or Thyroid Cancer Are More Likely to Develop the Other Type Later [AACR]

Cancer deaths fall 10 per cent in a decade - but alcohol fuels rise in liver cases [The Telegraph]

Many cancer survivors face increased risk of heart disease [Reuters]

6.10 Politiques

Clinton, Sanders trade barbs over special interest money from drug companies [STAT]

After The Martin Shkreli Circus, How Can We Fix Drug Pricing? [Forbes]

6.11 Patients

Well: Living With Cancer: A Woman Like Me [NY Times]

6.6 Publications

Let’s just try that again [The Economist]

If you fail to reproduce another scientist’s results, this journal wants to know [Science]

Biotech giant publishes failures to confirm high-profile science [Nature News & Comment]

6.7 DMP, Big Data & applis

Three Industry Leaders Join the CancerLinQ™ Team to Help Guide Big-Data Initiative [ASCO]

6.9 Controverses

Should biologists stop grouping us by race? [STAT]