lundi 29 février 2016

Onco Actu du 29 février 2016

1. Biologie

Researchers discover pancreatic cancer is 'four different diseases' [NHS Choices]

The Bigger Picture - Finding the 10%: what 'essential genes' mean for cancer [The Institute of Cancer Research]

Researchers find link between death of tumor-support cells and cancer metastasis [National Institutes of Health]

2. Etiologie

Chemical found in babies' dummies and condoms 'probably causes cancer' [The Telegraph]

Big verdict doesn't assure more wins for plaintiffs in talc-cancer cases [Reuters]

Whole-Genome Study Allays Cancer Fears Surrounding Stem Cell Techniques [GEN]

Cancer questions over popular diabetes drugs raise furor []

3. Prévention

Air pollution 'kills 40,000 a year' in the UK, says report [NHS Choices]

Air pollution, health and cancer – a new report calls for action [Cancer Research UK]

Smoking v. Obesity: The Economics Of Prevention And Its Dependence On Treatment [Health Affairs]

3.2 Prévention - Obésité

Childhood obesity: the task of tackling cancer begins early [Cancer Research UK]

3.3 Prévention - Vaccins

HPV vaccine tied to drop in cases but many U.S. kids still unprotected [Reuters]

3.5 Prévention - UV

AACR Joins With Melanoma Experts to Warn of Dangers from Tanning Beds [CANCER RESEARCH Catalyst]

3.6 Prévention - Activité physique

A run a day keeps the tumour at bay [The Economist]

4. Dépistage, diagnostic et pronostic

More PET scans may not help lung, esophageal cancer survivors [Reuters]

4.10 Dép., diag. & prono. - Poumon

Myriad Genetics Expands Strategic Research Collaboration With AbbVie [Myriad]

4.12 Biopsies liquides

Blood test that reveals 'true age' shows risk of dying from cancer [The Telegraph]

4.5 Dép., diag. & prono. - Colorectal

Colonoscopies: America’s gold standard, while Canada says they’re not justified [HealthNewsReview]

Canadian experts say 'no' to colonoscopy for colon cancer screening [Reuters]

4.9 Dép., diag. & prono. - Sein

Study Suggests Many Women with Early Breast Cancer Receive Unnecessary Imaging Tests [ASCO]

Breast cancer 'first response' at 10-year low [BBC News]

Myriad Expands Diagnostic Research Collaboration With TESARO and Merck [Myriad]

5. Traitements

Moving away from the ‘one fraction size fits all' approach to radiotherapy [The Institute of Cancer Research]

‘Controlling’ tumours with chemo may help manage some cancers long-term [Cancer Research UK]

5.10 Traitements - Essais

Reporting results from clinical trials is vital for science-based medicine [Science-Based Medicine]

Academics fall short in reporting results of clinical trials [Nature News & Comment]

5.12 Immunothérapies

Stanford Spins Out Immunotherapy Work Funded By CIRM's Millions [Xconomy]

Rivals chase Bristol-Myers in cancer immunotherapy drug race [Reuters]

Opening a window of opportunity for head and neck cancer [Cancer Research UK]

5.12.1 Immunothérapies - partenariats

Juno Therapeutics, Seattle Cancer Care Alliance and Fred Hutchinson Cancer Research Center Announce New Immuno-oncology Clinical Trials Unit [Juno Therapeutics]

5.12.2 Immunothérapies - CAR-T

Science Talk - CAR T cell immunotherapy: on the road towards a cancer cure? [The Institute of Cancer Research]

CAR Trials Drive Leukemia and Lymphoma Treatment in New Direction [UC San Diego Health]

5.2 Pharma

Ignyta dumps some Teva cancer drugs to focus on its top prospects [FierceBiotech]

Novartis drug PKC412 (midostaurin) receives Breakthrough Therapy designation from the FDA for newly-diagnosed FLT3-mutated acute myeloid leukemia (AML) [Novartis]

5.3 Traitements - FDA, EMA,...

Senate Confirms Califf as Next FDA Commissioner [RAPS]

Rejected Therapy Reveals Inconsistency of FDA Procedures for Drugs, Immunotherapies [The Cancer Letter]

5.3.4 Traitements - AMM (FDA, EMA)

Pfizer Receives Expanded FDA Approval For IBRANCE (palbociclib) In HR+, HER2- Metastatic Breast Cancer [Pfizer]

5.4 Traitements - Economie

NHS plan to reassess value of cancer drugs alarms patient groups [The Guardian]

New NHS cancer drugs fund approved [BBC News]

The Cancer Drugs Fund: saviour or stumbling block? [PHG Foundation]

The case for rationing: Why we should limit public spending on cancer drugs [STAT]

Online Tool Improves Access to Information on Cancer Treatment Costs [ASCO]

Why We Need to Start Putting a Price on Human Life [Wall Street Journal]

5.5 ASCO

2016 Symposium Highlights Notable Research Advances in Quality of Cancer Care [ASCO]

6. Lutte contre les cancers

The EurOPDX Consortium [ESMO]

6.1 Observation

Childhood leukemia patients from low-income areas relapse earlier, study finds [The Guardian]

Trend: Mastectomies Are Becoming Outpatient Surgery [NPR]

6.10 Politiques

On precision medicine, Obama is playing the long game [STAT]

Preparing to Launch the Precision Medicine Initiative Cohort Program [National Institutes of Health]

Obama Is Using The Bully Pulpit To Set Patient Data Free [Forbes]

6.11 Patients

Cordelia Galgut: Why are the long term effects of cancer so rarely talked about? [BMJ Blogs]

6.5 Médecines alternatives

Hillary Clinton and Bernie Sanders: Embracing “integrative medicine” quackery? [Respectful Insolence]

6.6 Publications

A Rainbow Unicorn Wants to Transform Biology Publishing [WIRED]

Journal retracts 7 papers by MD Anderson cancer researcher long under investigation [Retraction Watch]

I’m Excited! A Post Pre-Print-Posting-Powwow Post [it is NOT junk]

6.7.2 Applis

App launched to help doctors spot cancer signs [BBC News]

6.9 Controverses

Thousands of goats and rabbits vanish from major biotech lab [Nature News & Comment]