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1. Biologie
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3.1 Tabac
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3.5 Prévention - UV
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4.12 Biopsies liquides
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5. Traitements
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The Chloroquine Story in Cancer Continues [In the Pipeline]
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Almost
immediately after Pfizer and Novartis provided evidence that
chloroquine (used in several chemotherapy regimes) doesn’t do what
people thought, another drug company (AstraZeneca, along with coworkers
at Dundee) is out with a paper suggesting what it might be doing
instead. The answer, if it’s the answer, is not an obvious one.
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Nano-caging gives a failed cancer drug new life [STAT]
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Scientists
from BIND joined forces with a team from AstraZeneca to take a cancer
drug the British pharmaceutical company had essentially abandoned,
encase it in a molecular cage called a nanoparticle, and give it to lab
rodents implanted with human cancers. Compared to the uncaged drug, the
nano-enclosed version was more effective and less toxic.
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Academic Research in Breast Cancer [ESMO]
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In
2015, academic-led trials provided evidence for safe de-escalation of
adjuvant treatment in early stage breast cancer and answered important
questions related to adjuvant regional irradiation and optimal
first-line chemotherapy in advanced-stage disease. The impact of such
studies that will affect clinical practice is summarized in an excellent
article by Martine Piccart and Isabelle Gingras, published in the
Nature Reviews Clinical Oncology.
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5.2 Pharma
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5.2.3 Pharma - économie
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5.3 Traitements - FDA, EMA,...
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6.1 Observation
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Cancer Surgery At Low-Volume Hospitals In California [Health Affairs]
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Even
with these approaches, there will continue to be difficulties. Some
patients may not be easily able to travel, even seemingly short
distances. Provisions need to be made for starting new surgical
programs. Measurement of volume may be best done in the context of the
collection of a range of quality data. But much more could and should be
done to track, report, and act on hospital volumes for important
surgeries.
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6.10 Politiques
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6.3 Associations
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Groups push pharma agenda under the guise of patient advocacy [HealthNewsReview]
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Astroturfers
gather ordinary citizens from the grassroots to advocate for various
causes while in reality shilling for the trade associations, PR firms,
corporations, and political organizations that set them up. Now along
comes a new patient advocacy organization, Patients Rising and its
sister group Patients Rising Now, which debuted in late summer shortly
after the House of Representatives passed the 21st Century Cures Act.
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6.6 Publications
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6.8 Communication
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Press releases stink. Here’s why that matters [STAT]
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To
be sure, good university press releases do serve a useful purpose by
informing reporters of potentially newsworthy developments. The trouble
comes when credulous journalists accept these notices without skepticism
— turning them from springboards to stories into stories themselves.
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