lundi 14 décembre 2015

Onco Actu du 14 décembre 2015

1. Biologie

With potential to save lives, CRISPR already sparing mice [STAT]

3.1 Tabac

What to make of tobacco industry research declarations of ‘no conflicts of interest’? [The Conversation]

What's Inside E-Cigarette Juice: Alcohol, More Alcohol, and Lots of Secrets [WIRED]

4.13 Dép., diag. & prono. - Peau

Jury still out on routine skin cancer screening [Reuters]

5.12 Immunothérapies

Scientists genetically engineer patients’ own cells to attack cancer [Wellcome Trust]

5.2 Pharma

Roche adds another positive snapshot for its PD-L1 checkpoint star 'atezo' [FierceBiotech]

5.2.2 Pharma - Fusions & Acquisitions

AstraZeneca looks to bag Imbruvica rival in $5B-plus Acerta buyout: Report [FierceBiotech]

5.3.4 Traitements - AMM (FDA, EMA)

FDA approves first emergency treatment for overdose of certain types of chemotherapy [FDA]

FDA approves new oral therapy to treat ALK-positive lung cancer [FDA]

FDA Grants Genentech’s Alecensa® (Alectinib) Accelerated Approval for People with a Specific Type of Lung Cancer [Genentech]

Roche gets accelerated U.S. approval for lung cancer drug [Reuters]

5.4 Traitements - Economie

ARIAD Announces Pricing and Reimbursement Negotiations for Iclusig in France to Continue into 2016 [ARIAD Pharmaceuticals]

Ovarian cancer drug wins NICE approval [Cancer Research UK]

5.7.1 SABCS-communiqués

Puma Biotechnology Presents 3-Year Disease Free Survival Data from Phase III Trial of PB272 in Extended Adjuvant Breast Cancer (ExteNET Trial) at the 2015 San Antonio Breast Cancer Symposium [Puma Biotechnology]

5.7.2 SABCS-divers

Alternative to tamoxifen may be preferable for women with early signs of breast cancer [Cancer Research UK]

Why Prolia May Be The Better Drug For Reducing Bone Breaks And Recurrence After Breast Cancer [Forbes]


SABCS 2015: Less Treatment Is More for Early-stage Breast Cancer [CANCER RESEARCH Catalyst]

Phase III BELLE-2 Trial Meets Primary Endpoint of Progression-free Survival [AACR]

6. Lutte contre les cancers

Cancer Screening, Prevention & Treatment in People with Mental Illness [ACS]

European cancer centers of excellence: powering long-term collaborative partnerships [Vall d'Hebron Institute of Oncology]

6.1 Observation

​Cancer Rates Decline in Many High-income Countries, but Rise in Lower-income Countries [AACR]

6.9 Controverses

Law ignored, patients at risk [STAT]