Onco Actu du 30 novembre 2015

	3.3 Prévention - Vaccins
Misleading HPV vaccine websites are easy to find [Reuters] The Internet, where the vast majority of Americans go for answers to a wide variety of medical questions, may be particularly misleading when it comes to facts about HPV, researchers report in the Journal of Adolescent Health.
	4. Dépistage, diagnostic et pronostic
2016 Global Tumor Marker Testing Market: Supplier Shares by Test, Country Volume and Sales Segment Forecasts, Innovative Technologies, Instrumentation Review, Competitive Strategies, Emerging Opportunities [ResearchAndMarkets] Anticipated technological breakthroughs will create numerous opportunities for determining genetic predisposition, detecting specific tumors, and monitoring biological response to cancer therapy. The rise in geriatric population will further compound the growing demand for malignancy assays and the rapid market expansion worldwide.
	5.12 Immunothérapies
Immunotoxins show anti-cancer synergy with immune checkpoint inhibitors [NIHilist's Immunology] Surprisingly, the authors noticed that combo therapy, that fully protected mice against tumors, actually increased infiltration of tumor tissue by functioning Foxp3+ T cells [in addition to conventional T cells]. This was counter-intuitive.
	5.2 Pharma
Bristol-Myers Squibb Announces Regulatory Update for Opdivo (nivolumab) in Advanced Melanoma [BMS] Bristol-Myers Squibb is working to evaluate the request outlined by the FDA and will continue to work closely with the agency to determine whether additional data, currently under review, adequately addresses these comments.
FDA declines expanded approval for Bristol-Myers' Opdivo drug [Reuters] The FDA approved Opdivo as a single agent for the treatment of patients with BRAF V600 wild-type melanoma earlier this week, but on Friday declined the approval of the drug for treating BRAF V600 mutation positive metastatic melanoma.
	5.2.3 Pharma - économie
Dr. Patrick Soon-Shiong is postponing IPO of healthcare data company NantHealth [LA Times] Soon-Shiong has already been stung by that downturn. NantKwest Inc., a developer of cancer therapies that he controls and is closely tied to NantHealth, has shed more than $1 billion in market capitalization since its July IPO.
	5.3 Traitements - FDA, EMA,...
Safer use of medicines by preventing medication errors [EMA] EMA makes new webpage and good practice guide available.
	5.8.2 ASH - Pharma
Bayer and Novartis to debut new data at ASH 2015 [Pharmafile] Pharma firms will present clinical trial results for the pipeline drugs they are pinning their 2016 hopes for success on, at the American Society of Haematology annual meeting in Orlando on December 5-8.
	6. Lutte contre les cancers
Mouth cancer: dentists and GPs should be able to refer patients straight for tests [Cancer Research UK] To help GPs and dentists diagnose patients faster, we recently launched our new Oral Cancer Toolkit in partnership with the British Dental Association and the Royal College of General Practitioners. Here, Professor Richard Shaw, a mouth cancer specialist who helped create it, explains why the toolkit recommends a departure from the recently published NICE referral guidelines.
Expert Opinion – Professor Richard Gilbertson talks children’s cancers [Cancer Research UK] It was a struggle to give up seeing patients because I absolutely loved clinical medicine, but I felt that the lab, rather than the clinic, was the place I could have the greatest impact for all children with brain tumours, wherever they lived. The lab was where I was most likely to achieve that 15 per cent drop in mortality.
	6.11 Patients
How do you tell your children you have cancer? [The Guardian] Fearing that I would mess up the task, I promptly suggested the help of a skilled psychologist but Karen wasn’t interested. “I’m too tired, doctor. Plus, you’re a mom, so you must have some idea about what to say to the kids. I just want you to guide me through it.”
	6.4 Médico-éco
Thousands of cancer patients 'too poor to celebrate Christmas' [The Guardian] Macmillan said the government must rethink its plan on welfare, which it said would take £30 a week away from people with cancer who are too ill to work.
	6.7.2 Applis
Mobile medical apps growing, but many lack proof that they work [Modern Healthcare] “There are a lot of untested apps on the market that may be unreliable or even dangerous,” Diamond said. If treatment is prescribed based on the wrong data, the provider could be found liable, though she knows of no such cases so far.