Onco Actu du 6 octobre 2015

	1. Biologie
Identifying cancer’s food sensors may help to halt tumour growth [University of Oxford] Oxford University researchers have identified a protein used by tumours to help them detect food supplies. Initial studies show that targeting the protein could restrict cancerous cells’ ability to grow.
	5.2 Pharma
Roche says data shows Cotellic combination therapy effective [Reuters] Last month, an EU advisory panel recommended Cotellic in combination with Zelboraf. A decision by the European Commission is expected by the end of 2015.
	5.3.4 Traitements - AMM (FDA, EMA)
FDA approves expanded indication for medical device to treat a form of brain cancer [FDA] When using Optune, a health care professional places electrodes on the surface of the patient’s scalp to deliver low-intensity, alternating electrical fields called “tumor treatment fields” (TTFields). The unique shape and special characteristics of rapidly dividing tumor cells make them susceptible to damage when exposed to TTFields, which could halt tumor growth.
Dako Announces FDA Approval of New Companion Diagnostic for Lung Cancer [Dako] The approval of PD-L1 IHC 22C3 pharmDx strengthens Dako’s portfolio of companion diagnostics and the company’s leadership position in developing and commercializing companion diagnostic products.
	5.5 ASCO
New Evidence for a Strategy to Identify Patients Nearing the End of Life [ASCO] The Surprise Question ─ “Would you be surprised if this patient died within the next year?” ─ was developed in the 1990s. Until now, however, there has been limited evidence of its utility in the cancer care setting.
Innovative Collaboration Among Radiation Oncologists and Palliative Care Specialists Improves Care for Patients With Advanced Cancer [ASCO] The service model is available to all patients with any type of cancer receiving radiation for palliative purposes, whether it is for metastases in the bone, brain, lung, pelvis, or any other organ system in the body. The current study focused on patients with painful bone metastases.
Panel Recommends Primary Palliative Care Services for Medical Oncology Practices [ASCO] A new guidance statement from the American Society of Clinical Oncology and the American Academy of Hospice and Palliative Medicine is being presented for the first time at the 2015 Palliative Care in Oncology Symposium in Boston.
	5.6 ESMO
Progress is made at the boundaries of disciplines [The Cancer Blog] I’m left wondering why so few people turned up to the session, even though its billing as a joint ASCO–ECCO symposium should have flagged up the importance of the topic. Was I witnessing the silo mentality in action?
	6. Lutte contre les cancers
Counting lumps in the lawn: a look back at the 1975 Nobel Prize [Cancer Research UK] It’s Nobel time again. So here at Cancer Research UK, we thought we’d look back at our own Nobel history, and at the very first of our amazing tally of six Nobel Laureates: Renato Dulbecco, who was deputy director of our London Research Institute between 1971 and 1977.
	6.8 Communication
Asking the dumb questions - Best-Cancer-Reporter-Award [Cancer World] When interviewed for Cancer World in 2007 Leaf observed that many of his critics were predicting that the big cancer breakthroughs would come by 2015. A quick look at the calendar would suggest that, unlike his magazine, his critics have missed a deadline.