Onco Actu du 1er septembre 2015

	3.1 Tabac
The U.S. Smoking Rate Just Hit A Historic Low [Huffington Post] New survey data, which the U.S. Centers for Disease Control and Prevention released Tuesday morning, suggests that just 15.2 percent of American adults are now using cigarettes on a regular basis. That smoking rate is nearly 2 percentage points lower than what the same survey reported for calendar year 2014.
	4. Dépistage, diagnostic et pronostic
A high-resolution X-ray source for medical imaging [Max-Planck-Gesellschaft] A laser-driven X-ray source makes it possible to produce very high-resolution images of tissues such as tumours.
	4.2 Dép., diag. & prono. - Génome
ASCO Releases Updated Policy Statement on Genetic and Genomic Testing for Cancer Susceptibility [ASCO] Published in the Journal of Clinical Oncology, the statement reviews the ways in which new technologies are transforming the assessment and identification of inherited cancer susceptibility, and makes a series of recommendations for the optimal deployment of these technologies in oncology practice.
New guidelines for cancer doctors aim to make sense of gene tests [Reuters] CHICAGO The American Society of Clinical Oncology (ASCO) has issued guidelines on how cancer doctors should approach the use of new genetic tests that screen for multiple cancer genes at the same time, including counseling patients about genes whose contribution to cancer is still poorly understood.
	5. Traitements
Mayo researchers examine risk factors and patient outcomes associated with colorectal cancer operations, identify benchmarks [Mayo Clinic] “Our findings also show that performing pre-operative risk assessments on patients who require both liver and colorectal resections could allow surgeons to more accurately predict patient outcomes and assist in preoperative planning and counseling these patients.”
	5.2.2 Pharma - Fusions & Acquisitions
Baxalta Said in Talks to Buy Ariad to Boost Cancer Offerings [Bloomberg] Baxalta Inc., the drugmaker fending off a $30 billion takeover offer from Shire Plc, is in talks to acquire Ariad Pharmaceuticals Inc. to boost its oncology business, people with knowledge of the matter said.
	5.3.4 Traitements - AMM (FDA, EMA)
Novartis receives EU approval for Tafinlar® and Mekinist®, first combination approved for patients with aggressive form of melanoma [Novartis] Approval based on two Phase III studies demonstrating statistically significant overall survival benefit with combination therapy vs BRAF inhibitor monotherapy.
	5.5 ASCO
ASCO Updates Guideline on Therapy for Advanced Lung Cancer [ASCO] To develop this clinical practice guideline update, an ASCO Expert Panel conducted a formal systematic review of relevant medical literature published from January 2007 through February 2014.
	6. Lutte contre les cancers
Newly funded research – understanding cancer at the population level [Cancer Research UK] The committee meets twice a year, and is in charge of an annual budget of around £2m. Here are some of the highlights of the new population research projects we funded after the last meeting, in April 2015...
“Precision medicine”: Hope, hype, or both? [Science-Based Medicine] To me, when new tests or factors that predict prognosis or response to therapy or suggest which therapies are likely to be most effective are developed and validated, it’s an artificial distinction to link them to genomics, proteomics, or whatever, as well as “big data” and refer to them as “precision medicine.” To me, medicine that works is just “medicine.”
Stigma around gynaecological cancer stopping women from visiting GP [The Guardian] The reluctance to do so was most prevalent among those aged 46 to 55, the age group most likely to ignore symptoms or think they were not serious enough to visit a GP.
	6.1 Observation
Men with Low-Risk Prostate Cancer in Active Surveillance Program Not Likely to Succumb to the Disease, Study Shows [Johns Hopkins] Data on long-term outcomes of 1,298 men point to value of surveillance versus surgery or radiation for some, say Johns Hopkins researchers.
Fukushima-related child cancers unlikely to rise: IAEA [Reuters] Adding to the uncertainty was the fact that the administration of "stable iodine" to protect children's thyroid glands was not done uniformly at the time, "primarily due to the lack of detailed arrangements," the report said.