mardi 21 juillet 2015

Onco Actu du 21 juillet 2015

1. Biologie

Shape-shifting molecular cousins are the key to DNA repair [Cancer Research UK]

2. Etiologie

Poor sleeping patterns link to cancer [BBC News]

3.1 Tabac

Brighton could be the first UK city to ban smoking on the beach [The Telegraph]

4. Dépistage, diagnostic et pronostic

Pill on a string can detect throat cancer without need for biopsy [The Telegraph]

4.12 Biopsies liquides

Liquid Biopsy the Key to ‘Active Surveillance’ of Cancer, Guardant Health Says [Wall Street Journal]

5. Traitements

Promise of precision medicine for common type of lymphoma [National Cancer Institute]

5.12 Immunothérapies

Adaptimmune touts a promising snapshot of TCRs for myeloma [FierceBiotech]

5.2 Pharma

CheckMate -025, a Pivotal Phase III Opdivo (nivolumab) Renal Cell Cancer Trial, Stopped Early [BMS]

Exelixis Announces Positive Top-Line Results from METEOR, the Phase 3 Pivotal Trial of Cabozantinib versus Everolimus in Patients with Metastatic Renal Cell Carcinoma [Exelixis]

Phase III Trial Shows Nivolumab Improves Survival in Advanced Kidney Cancer [Cancer Research Institute Blog]

Exelixis Scores Much-Needed Kidney Cancer Study Win to Boost Drug Sales [TheStreet]

Exelixis Drug Slows Kidney Cancer In New Chance For Embattled Biotech [Forbes]

Bristol-Myers' Opdivo found effective in kidney cancer [Reuters]

5.2.1 Pharma - Partenariats

GSK, Pfizer, AstraZeneca collaborations tilt U.K. academics to Big Pharma [FierceBiotech]

Agenus Acquires Novel Antibodies to Immuno-oncology Target CEACAM1 [Agenus]

5.2.3 Pharma - économie

Genzyme’s family tree: How Henri Termeer spawned network of Genzyme alums leading dozens of biotechs from Cambridge to Stockholm [The Boston Globe]

5.3.4 Traitements - AMM (FDA, EMA)

European Imbruvica approval for Janssen [Pharmafile]

European Commission Approves Nivolumab BMS, the First PD-1 Immune Checkpoint Inhibitor in Europe Proven to Extend Survival for Patients with Previously-Treated Advanced Squamous Non-Small Cell Lung Cancer [BMS]

5.4 Traitements - Economie

Rising U.S. Drug Prices Are Focus of Research Grant [Wall Street Journal]

5.5 ASCO

ASCO Attendees Anticipate Increasing Use of Molecular Diagnostics Over Next Decade [The OBR Blog]

ASCO Urges Expansion of Cancer Research to Include More Older Adults [ASCO]

6. Lutte contre les cancers

The rocky road to developing new children’s cancer treatments [The Institute of Cancer Research]

Children’s Cancer Is Unprofitable and Ignored [Newsweek]

Comprehensive Cancer Care for Children and Their Families: Summary of a Joint Workshop by the Institute of Medicine and the American Cancer Society [The National Academies Press]

The vitamin D question: what's the best advice? [Cancer World]

6.1 Observation

MD Anderson study finds one-third of colorectal cancers diagnosed before age 35 are hereditary [MD Anderson Cancer Center]

Survival patterns in U.S. women with invasive breast cancer [National Cancer Institute]

6.11 Patients

Meeting A Stem Cell/Bone Marrow Donor Reminds Us All About Ordinary People Doing Something Extraordinary [Dr Len]

6.6 Publications

Gynecologic cancer researcher up to 13 retractions [Retraction Watch]

6.7 DMP, Big Data & applis

Team links gene expression, immune system with cancer survival rates [Stanford Medicine]

The 'LinkedIn' for Cancer [Newsweek]

6.8 Communication

UK experts demand reinstigation of 'shelved' lung cancer awareness campaign [ecancer - News]

6.9 Controverses

New York Attorney General Accuses Brooklyn Children’s Charity of Fraud [NY Times]