vendredi 10 juillet 2015

Onco Actu du 10 juillet 2015

1. Biologie

‘Jumping genes’ may drive oesophageal cancer [Cancer Research UK]

2.7 Etiologie - Obésité

Overweight teenagers in denial about obesity at risk of up to 10 different types of cancer [The Telegraph]

3. Prévention

Op-Ed Contributor: Why Is the Federal Government Afraid of Fat? [NY Times]

3.1 Tabac

Exclusive: With feds slow to act, states target e-cigarette sales to minors [Reuters]

4. Dépistage, diagnostic et pronostic

Want Answers? Look to the Non-Coding Region of the Genome, Says Cancer Researcher, Tim Triche [Mendelspod]

4.2 Dép., diag. & prono. - Génome

Study Advances Potential of Tumor Genome Sequencing and DNA-Based Blood Tests in Precision Treatment and Detection of Pancreatic Cancer [Johns Hopkins]

Exciting developments in Pancreatic Cancer [CoreGenomics]

4.9 Dép., diag. & prono. - Sein

Why Women Shouldn't Cower To Concerns About Overdiagnosis Of Breast Cancer [Forbes]

5. Traitements

Less intensive chemo avoids irreversible side effects in children’s cancer [Cancer Research UK]

Colourful chemotherapy [The Economist]

5.2 Pharma

Soon-Shiong spawns yet another spinout in a tangled web of cancer R&D [FierceBiotech]

5.2.1 Pharma - Partenariats

Epizyme Extends Celgene Cancer Deal for $10M Upfront [Xconomy]

Cancer Research UK and Cancer Research Technology announce partnership with Monopar Therapeutics to develop new oncology compound [Cancer Research UK]

5.3.4 Traitements - AMM (FDA, EMA)

Eli Lilly gains FDA advisers' support for a questionable lung cancer drug [FierceBiotech]

Lilly Statement on FDA Advisory Committee Review of Necitumumab [Lilly]

FDA panel: Lilly cancer drug has positive risk/benefit profile [Reuters]

5.4 Traitements - Economie

Payers think they can squeeze prices on cancer immunotherapies? Not so fast, analyst says [FiercePharma]

6. Lutte contre les cancers

Teens Dying Of Cancer Face Intensive Treatments In The Final Days [NPR]

Aggressive Cancer Treatment Near End of Life Persists Despite Rise in Advance Planning Efforts [Johns Hopkins]

6.10 Politiques

ACT NOW: Encourage Your Representative to Vote for 21st Century Cures Legislation [ASCO]

This bill promises to speed up drug approvals so much that it’s making people uncomfortable [The Washington Post]

6.11 Patients

Run for your life: why cancer treatments won't stop me [The Guardian]

6.6 Publications

The Metric Tide: Rethinking Research on Research [Wellcome Trust Blog]

There are powerful currents whipping up the metric tide. The HEFCE metrics report [DC's Improbable Science]

The metric tide: an agenda for responsible indicators in research [The Guardian]

6.7 DMP, Big Data & applis

The problem with guidelines: epidemiological risks and decisions about individual patients [The Incidental Economist]

6.7.1 Bioinformatique

World-leading Big Data researchers call for support for more accessible and more effective storage of data in the cloud to facilitate genomics research [Broad Institute of MIT and Harvard]

6.7.3 DMP

The Many Challenges But Promise of Big Data [Clinical Oncology News]