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3. Prévention
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3.1 Tabac
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3.3 Prévention - Vaccins
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4.2 Dép., diag. & prono. - Génome
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5. Traitements
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The Basket Trial: An Evolving Clinical Trial Design [The ASCO Post]
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Results
of the CUSTOM trial reveal key strengths of the basket trial design as
well as some challenges. It is notable that a basket trial strategy can
be used not only to validate a clinical target but also to identify a
favorable response to targeted therapy in a small number of patients.
However, at the same time, CUSTOM was unable to complete accrual to 13
of 15 planned study arms, and one of the arms that did complete accrual
(selumetinib in NSCLC) did not achieve its primary endpoint.
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5.2 Pharma
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5.2.1 Pharma - Partenariats
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5.5 ASCO
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5.5.5 ASCO (gastro-intestinal)
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6. Lutte contre les cancers
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Back to the Future: Volume as a Quality Metric [news@JAMA]
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We
know that when patients receive these surgeries at low-volume
institutions or in the hands of low-volume surgeons, they tend to fare
worse. What’s remarkable isn’t that these leaders asked hospitals to
focus on volume as a way to improve patient outcomes, but that they are
doing it in 2015.
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6.7 DMP, Big Data & applis
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