mardi 19 mai 2015

Onco Actu du 19 mai 2015

1. Biologie

Study may explain mysterious cancer–day care connection [Science]

4.1 Dép., diag. & prono. - Prostate

Urine-based test improves on PSA for detecting prostate cancer [University of Michigan Comprehensive Cancer Center]

Prostate Cancer Testing Drops Off After Controversial Guidelines [US News]

4.10 Dép., diag. & prono. - FDA, EMA, NICE,...

I Love Them, I Love Them Not….. Proposed Revised Medicare Guidelines For Coverage of BRCA Testing [The DNA Exchange]

CMS Unveils Draft LCD for BRCA1 and BRCA2 Genetic Tests [GEN]

4.12 Biopsies liquides

New device successfully captures metastasis-associated circulating tumor cell clusters [Massachusetts General Hospital]

Genomic Health Advances Liquid Biopsy Pipeline, Shows Ability to Accurately Monitor Urine for Presence of Bladder Cancer [Genomic Health]

4.9 Dép., diag. & prono. - Sein

Extra radiology exams may only benefit some women with dense breasts [Reuters]

Change To Mammogram Guidelines Could Lead To Coverage Shift [NPR]

Study Finds Dense Breast Tissue Isn’t Always a High Cancer Risk [NY Times]

5. Traitements

UK-US study compares radiotherapy with proton therapy in childhood cancer [The Institute of Cancer Research]

Nanotherapy effective in mice with multiple myeloma [Washington University in St. Louis]

Targeting the supply lines: metabolic approaches to killing cancer cells [Cancer World]

5.12 Immunothérapies

Human Ingenuity Takes On Cancer’s Darwinian Ways [NY Times]

5.2 Pharma

Agios Announces FDA Fast Track Designation Granted to AG-120 for Treatment of Patients with Acute Myelogenous Leukemia with an IDH1 Mutation [Agios]

Immunomedics Awarded Fast Track Designation by FDA for Sacituzumab Govitecan for Non-Small Cell Lung Cancer Therapy [Immunomedics]

5.2.1 Pharma - Partenariats

Sorrento dives into immuno-oncology under Soon-Shiong's shadow [FierceBiotech] ASCO (général) - Industriels

Foundation Medicine and Collaborators to Present Data in 22 Oral and Poster Presentations at the 2015 ASCO Annual Meeting [Foundation Medicine]

6. Lutte contre les cancers

Gerstner Family Foundation commits $10 million to Broad Institute to overcome cancer drug resistance [Broad Institute of MIT and Harvard]

6.10 Politiques

Proposed cuts to Europe’s research budget – why we’re fighting back [Cancer Research UK]

As in 2014, “right-to-try” laws continue to metastasize in 2015 [Science-Based Medicine]

6.6 Publications

ORI-sanctioned former UT-Southwestern cancer researchers up to 10 retractions [Retraction Watch]

6.9 Controverses

Drug trials firm to challenge plans for greater transparency over results [The Guardian]