mercredi 13 mai 2015

Onco Actu du 13 mai 2015

1. Biologie

CRISPR Dips into Cancer’s Pockets of Vulnerability [GEN]

Cancer cells spread by “disguising themselves,” study shows [Scope Blog]

When defences attack: the hidden cause of cancer hiding in our cells [Cancer Research UK]

2. Etiologie

Hormone oestrogen linked to male breast cancer [NHS Choices]

Men with high oestrogen levels could be at greater risk of breast cancer [Cancer Research UK]

3.1 Tabac

Provinces move to regulate e-cigarettes as Ottawa studies issue [The Globe and Mail]

4.12 Biopsies liquides

EU consortium validates blood-based cancer biomarkers [ecancer - News]

4.2 Dép., diag. & prono. - Génome

Nascent Group Points to a Way To Validate, Pay for Genomic Tests [The Cancer Letter]

4.9 Dép., diag. & prono. - Sein

What We Might Learn From The Early-Stage Breast Cancer Disclosures Of Sandra Lee and Rita Wilson [Forbes]

New method detects more breast cancer in screening [EurekAlert!]

5. Traitements

First-in-class Antibody Mixture Shows Clinical Activity Against Treatment-resistant, Advanced Colorectal Cancer [AACR]

5.12 Immunothérapies

Talking Cure? For Cancer Immunotherapy, Still Many Rivers to Cross [Xconomy]

5.2 Pharma

Takeda Announces Termination of Alisertib Phase 3 Trial in Relapsed or Refractory Peripheral T-cell Lymphoma [Takeda]

NewLink's Pancreatic Cancer Vaccine on Long Road to Study Failure [TheStreet]

GSK's Curious Oncology Research Position -- A Recipe For Failure? [Forbes]

AstraZeneca digs into precision medicine with lung, heart deals [Reuters]

Merck KGaA, Threshold win fast track for pancreatic cancer drug [Reuters]

5.2.2 Pharma - Fusions & Acquisitions

Baxter pads biopharma unit with pre-spinoff oncology buy [FiercePharma]

Baxter BioScience to Expand Global Oncology Footprint with Acquisition of Oncaspar® Portfolio for Leukemia [baxter]

Juno beefs up its CAR-T arsenal with an $80M biotech buyout [FierceBiotech]

5.2.3 Pharma - économie

Soon-Shiong raises another $100M for his cancer-focused biotech [FierceBiotech]

5.4 Traitements - Economie

Number of Americans using $100,000 in medicines triples: Express Scripts [Reuters]

5.5 ASCO

ASCO 2015 Preview: A Panel Discussion of Clinical Presentations with High-Impact Potential [Kantar Health]

5.6 ESMO

Lower Radiation Doses May Be Sufficient For Treating Certain Cancers, Report IAEA Experts [ESMO]

6. Lutte contre les cancers

What exactly is personalised medicine? [ecancer education]

6.9 Controverses

N=1 drug trials: yet another form of legerdemain? [The Mermaid's Tale]