mardi 21 avril 2015

Onco Actu - Spécial AACR 2

5.9 AACR

American Association for Cancer Research Inaugurates New Leadership at 2015 Annual Meeting [AACR]

New SU2C-OCRF-OCNA-NOCC Ovarian Cancer Dream Team Announced; $6 Million Grant Over 3 Years Will Focus on DNA Repair Therapies [AACR]

5.9.1 AACR - sein

Adding the PI3K Inhibitor BYL719 to Letrozole Was Safe, With Early Signs of Activity Against Metastatic ER-positive Breast Cancer [AACR]

Dual mTOR Inhibitor-Fulvestrant Combo Feasible, With Clinical Benefit for Advanced Breast Cancer Patients [AACR]

Black Women Found to Have Denser Breast Tissue Than White Women [AACR]

New Antibody-Drug Conjugate Shows Early Promise for Patients With Metastatic HER2-positive Breast Cancer [AACR]

Investigational ER Degrader Safe, With Early Signs of Antitumor Activity Against Advanced ER-positive Breast Cancer [AACR]

Extended Overnight Fasting May Lead to Reduced Breast Cancer Risk [AACR]

Investigational PD-L1–targeted Immunotherapy Safe for Patients With Triple-negative Breast Cancer, Effective in Some [AACR]

Fasting at night lowers risk of breast cancer and diabetes [The Telegraph] AACR - sein (observation)

U.S. Breast Cancer Cases Expected to Increase by as Much as 50 Percent by 2030 [AACR]

Breast Cancer Cases To Increase 50% By 2030. Don't Panic. [Forbes]

Breast cancer cases in U.S. projected to rise as much as 50% by 2030 [LA Times]

5.9.3 AACR - mélanome

First Randomized Study Evaluating Opdivo (nivolumab)+Yervoy (ipilimumab) Regimen Demonstrates Superior Efficacy Versus Yervoy Alone in Patients with Previously Untreated Advanced Melanoma |[BMS]

Phase II Trial of Ipilimumab-Nivolumab Combo Shows Promise in Advanced Melanoma [AACR]

Immune System Drugs Melt Tumors In New Study, Leading A Cancer Revolution [Forbes]

Bristol-Myers immunotherapy combo promising in melanoma: study [Reuters]

5.9.4 AACR - poumon

New SU2C-American Cancer Society Lung Cancer Dream Team Announced [AACR]

'Liquid biopsy' picks up cancer biomarkers in blood, study finds [LA Times]

5.9.5 AACR - CAR-T

Novartis solid tumor 'CAR T cell' still holds promise: researcher [Reuters]

5.9.6 AACR - divers

Lilly Releases Early-Stage Pipeline Data at AACR Annual Meeting 2015 [Lilly]

Foundation Medicine and Collaborators to Present New Data in 12 Oral and Poster Presentations at the AACR Annual Meeting [Foundation Medicine]

Real-world Targeted Treatment Based on Whole Genome Sequencing Difficult in Pancreatic Cancer [AACR]

Time Bungles Precision Medicine [The Scientist]