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3.1 Tabac
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“Like
the consistent use needed with nicotine-replacement therapy (NRT), only
those who used tank-style e-cigarettes every day were more likely to
have quit smoking tobacco a year on".
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The
largest study of its kind to date finds smokers diagnosed with cancer
were more likely to quit than other smokers, supporting the hypothesis
that a cancer diagnosis is a “teachable moment” that can be used to
promote cessation.
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4.2 Dép., diag. & prono. - Génome
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Are
these data geeks really ready for the world of medical testing? Some
big-name scientific collaborators say yes. One is Mary Claire King, who
pioneered the study of the BRCA genes and has bristled at the high price
of the tests. Another is Laura Esserman, director of the Carol Franc
Buck Breast Care Center at the University of California, San Francisco.
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BRCA Share™ is a novel public-private initiative designed to enhance the clarity and quality of patient testing
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Color
Genomic’s 19-gene panel test, and its accompanying advertising, focuses
heavily on the BRCA1 and BRCA2 gene mutations. The two risk factors
have received increased public attention since actor Angelina Jolie
cited the two gene mutations as important to her decision to undergo a
double mastectomy; an article by Jolie about her decision is quoted on
Color’s website).
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4.9 Dép., diag. & prono. - Sein
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While
empowering women to make an informed decision about screening is
laudable and something that the American Cancer Society also recommends,
we are concerned that the 'C' rating might lead to coverage for fewer
women and more out of pocket costs for women in their 40s.
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The
major media outlets all jumped in with coverage that — for the most
part — did reasonably thorough jobs of fulfilling our criteria for
health news stories.
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Each
time we screen 1000 women age 40-49, there are 121 false positives.
There are 10 biopsies that didn’t need to happen. There’s also one false
negative, or real breast cancer missed. That’s each time, not the whole
10 years.
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To
put these numbers into perspective, if an average 50-year-old woman has
a 2.38% chance of getting cancer in the next 10 years of her life, a
woman with the highest density breasts would have a 4.76% chance of
being diagnosed.
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5. Traitements
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Pharmacokinetics
within tumour cells play an important role in the development of
resistance. A better understanding of the mechanisms involved is
important for devising treatment strategies to extend tumour response.
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5.12 Immunothérapies
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There
were numerous presentations of clinical trials at various stages of
progress that are testing the potential of rational combinations of
immunotherapies and targeted therapies, as well as combinations of these
modern therapies with the traditional pillars of cancer treatment, such
as chemotherapy and hormone therapies.
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5.2 Pharma
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The
Phase 3 study has two primary endpoints, complete hematologic remission
rate and overall survival. Pfizer is continuing the study to allow for
the data on overall survival to mature.
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5.2.1 Pharma - Partenariats
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The
goal of the collaboration is to advance a portfolio consisting of
programs with novel mechanisms of action targeting immune checkpoint
pathways, co-stimulatory signals and regulatory T cells.
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5.3 Traitements - FDA, EMA,...
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The
Breakthrough Therapy designation was based on a data analysis from an
expansion cohort of a global Phase 1 study (Study 1001), which evaluated
XALKORI in 50 patients with ROS1-positive advanced NSCLC.
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5.4 Traitements - Economie
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So
if you’re shocked by the six-figure prices of cancer drugs that offer
marginal health benefits, brace yourself for what’s to come.
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5.5 ASCO
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The presscast will highlight studies representing the range of research being presented at the Annual Meeting
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6. Lutte contre les cancers
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The
Roswell Park Cancer Institute of Buffalo, New York, on Tuesday signed
an agreement with Cuba's Center for Molecular Immunology to develop a
lung cancer vaccine with a clinical trial in the United States, Roswell
Chief Executive Officer Candace Johnson said.
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6.1 Observation
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Large
Study Finds Fewer than One in Ten Prostate Cancer Patients with Adverse
Pathologic Features after Surgery Receive Radiation Therapy.
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Beating
Bowel Cancer found wide variation within the NHS in England in
diagnosing the disease. It says 3,200 lives could be saved each year if
every NHS region did as well as the best performing areas.
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6.11 Patients
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Gibson,
who built a wellness empire on the back of claims she cured terminal
brain cancer through diet and lifestyle, has admitted deceiving her
followers.
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