vendredi 17 avril 2015

Onco Actu du 17 avril 2015

1. Biologie

TRAIL and error – flipping cancer’s self-destruct switch [Cancer Research UK]

LabTV: Young Scientist Curious About How Cancer Cells Thrive [NIH Director's Blog]

Microscopy Opening Up New Cancer Discovery Avenues [National Cancer Institute]

Scientists find key to 'turbo-charging' immune system to kill all cancers [The Telegraph]

2.5 Etiologie - Gènes

NIH study finds genetic link for rare intestinal cancer [NIH]

Genomes carry a heavy burden [Nature News & Comment]

2.7 Etiologie - Obésité

Obesity significantly increases prostate cancer risk in African-American men, study finds [Fred Hutch]

Obesity link to prostate cancer may vary by race [Reuters]

3.1 Tabac

Regular e-cigarette use low among teens, analysis suggests [Cancer Research UK]

Tobacco Use Among Middle and High School Students — United States, 2011–2014 [CDC]

Use of E-Cigarettes Rises Sharply Among Teenagers, Report Says [NY Times]

E-cigarette use soared, smoking rate fell among U.S. youth in 2014: CDC [Reuters]

4. Dépistage, diagnostic et pronostic

Will more medical tests make us healthier? [CNN]

4.2 Dép., diag. & prono. - Génome

Cancer mutations often misidentified in the clinic [Nature News & Comment]

Make precision medicine work for cancer care [Nature News & Comment]

4.7 Dép., diag. & prono. - Col de l'utérus

Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology [Hologic]

4.9 Dép., diag. & prono. - Sein

Simple blood test for breast cancer could be more accurate than mammograms [The Telegraph]

5. Traitements

Immune-Based Treatment Shows Promise against Metastatic Cervical Cancer [National Cancer Institute]

5.3 Traitements - FDA, EMA,...

Selumetinib granted Orphan Drug Designation by US FDA for treatment of uveal melanoma [AstraZeneca]

5.4 Traitements - Economie

New Cures Require New Pricing Policies [Health Affairs Blog]

Cancer Growth Inhibitors Market & Clinical Pipeline Analysis [ResearchAndMarkets]

5.6 ESMO

ELCC 2015 News: EGFR Mutation Detection Possible from Ultrasound-Guided Fine Needle Aspirates Taken from Patients with Lung Cancer [ESMO]

ELCC 2015 News: Brigatinib (AP26113) Shows Intracranial Anti-tumour Activity in ALK-positive NSCLC patients with Brain Metastasis Following Crizotinib [ESMO]

ELCC 2015 News: VEGF SNPs Identified as Prognostic Markers for Bevacizumab Response in Patients with Advanced Non-Squamous NSCLC [ESMO]

AstraZeneca announces updated progression free survival data for investigational non-small cell lung cancer medicine AZD9291 [AstraZeneca]

ELCC 2015 News: Promising Results for Surgical Salvage of Local Recurrences after Stereotactic Ablative Radiotherapy in Patients With Early-Stage NSCLC [ESMO]

ELCC 2015 News: Neoadjuvant Erlotinib in Endobronchial Ultrasound Confirmed Stage IIIA-N2 NSCLC [ESMO]

ELCC 2015 News: Promising Clinical Activity Observed With Novel EGFR Inhibitor in Patients With Advanced NSCLC [ESMO]

ELCC 2015 Press Release: Evidence Grows that Melanoma Drugs Benefit some Lung Cancer Patients [ESMO]

ELCC 2015 News: ‘Real-World’ EGFR Mutation Frequency Results From a Large Population of Chemotherapy Naive Patients With Advanced NSCLC [ESMO]

ELCC 2015 News: Safety and Efficacy Results with Selected Doses From a Phase I/II Trial of AP26113 in Patients with Advanced Malignancies, Including ALK–Positive NSCLC [ESMO]

5.9 AACR

Seattle Genetics Highlights Broad Presence at the American Association for Cancer Research (AACR) Annual Meeting [Seattle Genetics]

6.11 Patients

Well: Living With Cancer: In and Out of the Closet [NY Times]