vendredi 15 novembre 2019

Onco Actu du 15 novembre 2019


1.4 BIOLOGIE - TECHNOS, MODÈLES



CRISPR's unwanted anniversary [Science]











3.1 PRÉVENTION - TABAC



Tobacco Product Use and Cessation Indicators Among Adults — United States, 2018 [CDC]











3.1.1 PRÉVENTION - TABAC - E-CIGS



U.S. vaping-related deaths rise to 42, cases of illness to 2,172 [Reuters]











3.6 PRÉVENTION - ACTIVITÉ PHYSIQUE



Exercise helps astronauts cope with side effects of spaceflight. Could it help cancer patients too? [STAT]











4.12 BIOPSIES LIQUIDES



Blood test for deadly eye melanoma [University of Queensland]











4.2 DÉP., DIAG. & PRONO. - GÉNOME



In France, it’s illegal for consumers to order a DNA spit kit. Activists are fighting over lifting the ban [STAT]










MSK-IMPACT AI Study Yields New Findings to Diagnose Tumor Types of Unknown Origin [AJMC]











4.5 DÉP., DIAG. & PRONO. - COLORECTAL



Early detection of colon cancer: When is the right time for the follow-up colonoscopy? [DKFZ]










Bowel cancer rates after colonoscopy vary by provider [University of Leeds]











5. TRAITEMENTS



Who shrank the drug factory? Briefcase-sized labs could transform medicine [Nature]











5.1 TRAITEMENTS - PRÉ-CLINIQUE



Blocking a survival mechanism could tackle melanoma treatment resistance [Cancer Research UK]











A step closer to can­cer pre­ci­sion medicine [University of Helsinki]











Researchers Halt Spread of Breast Cancer by Blocking Metastasis-Promoting Enzyme [UCSF]











5.12.11 IMMUNOTHÉRAPIES - PRÉ-CLINIQUE



Prostate cancer bone metastases thwart immunotherapy by producing TGF-β [MD Anderson Cancer Center]











5.12.13 IMMUNOTHÉRAPIES - BIOMARQUEURS



Findings could help identify which aggressive breast cancers will respond to immune treatments [UNC]











5.12.4 IMMUNOTHÉRAPIES - ESSAIS



Clinical Benefit of Pembrolizumab in Previously Treated Advanced MSI-H/dMMR Non-colorectal Cancers [ESMO]











5.12.7 IMMUNOTHÉRAPIES - VACCINS



Duke Researchers Find Simpler, More Effective Cancer Vaccine Approach [Duke]











5.2 PHARMA



AstraZeneca’s selumetinib moves past cancer failures to nab FDA priority review in neurofibromatosis [Fierce Pharma]











US FDA accepts regulatory submission for selumetinib in neurofibromatosis type 1 and grants Priority Review [AstraZeneca]











AstraZeneca, Merck win red carpet treatment at the FDA as a 3-time loser seeks speedy OK for rare tumors [EndPoints]











5.2.3 PHARMA - ÉCONOMIE



Teva to produce children's chemo drug again as shortage leads to backlash [Fierce Pharma]










Teva to restart production of cancer drug after shortages stressed treatment [Biopharma Dive]











Teva to Re-enter Pediatric Cancer Drug Market After Shortage Concerns [RAPS]











5.3.4 TRAITEMENTS - AMM (FDA, EMA,...)



U.S. FDA Grants BeiGene’s BRUKINSA™ (zanubrutinib) Accelerated Approval to Treat Adult Patients with Mantle Cell Lymphoma Who Received at Least One Prior Therapy [BeiGene]











China's BeiGene scores first-ever FDA approval — but can they carve up J&J's blockbuster franchise? [EndPoints]










FDA approves therapy to treat patients with relapsed and refractory mantle cell lymphoma supported by clinical trial results showing high response rate of tumor shrinkage [FDA]











China's BeiGene gets FDA approval for drug to treat rare form of lymphoma [Reuters]











6.7 DMP, BIG DATA & APPLIS



I'm the Google whistleblower. The medical data of millions of Americans is at risk [The Guardian]










Growing Field of Cardio-Oncology Boosted by Collaboration Between Leading Oncology and Cardiovascular Health Organizations [ASCO]











6.7.3 DMP



Yale study: Doctors give electronic health records an ‘F’ [Yale]